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Draft Genome Sequences of Two Serotype 19A Sequence Type 226 Clinical Isolates from Hungary, Hu17 with High-Level Beta-Lactam Resistance and Hu15 of a Penicillin-Sensitive Phenotype.来自匈牙利的两株血清型19A序列型226临床分离株的基因组序列草图,Hu17具有高水平β-内酰胺抗性,Hu15为青霉素敏感表型。
Genome Announc. 2017 May 18;5(20):e00401-17. doi: 10.1128/genomeA.00401-17.
2
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Antimicrob Agents Chemother. 2017 Jun 27;61(7). doi: 10.1128/AAC.00414-17. Print 2017 Jul.
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Penicillin-binding proteins as resistance determinants in clinical isolates of Streptococcus pneumoniae.肺炎链球菌临床分离株中作为耐药决定因素的青霉素结合蛋白
Microb Drug Resist. 1996 Summer;2(2):177-81. doi: 10.1089/mdr.1996.2.177.
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引用本文的文献

1
New Aspects of the Interplay between Penicillin Binding Proteins, , and the Two-Component System CiaRH of Penicillin-Resistant Streptococcus pneumoniae Serotype 19A Isolates from Hungary.匈牙利19A血清型耐青霉素肺炎链球菌中青霉素结合蛋白与双组分系统CiaRH相互作用的新方面
Antimicrob Agents Chemother. 2017 Jun 27;61(7). doi: 10.1128/AAC.00414-17. Print 2017 Jul.

本文引用的文献

1
Parallel evolution of Streptococcus pneumoniae and Streptococcus mitis to pathogenic and mutualistic lifestyles.肺炎链球菌和缓症链球菌向致病和共生生活方式的平行进化。
mBio. 2014 Jul 22;5(4):e01490-14. doi: 10.1128/mBio.01490-14.
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RATT: Rapid Annotation Transfer Tool.RATT:快速注释转移工具。
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Identification of the genes directly controlled by the response regulator CiaR in Streptococcus pneumoniae: five out of 15 promoters drive expression of small non-coding RNAs.肺炎链球菌中由应答调节因子CiaR直接调控的基因鉴定:15个启动子中有5个驱动小非编码RNA的表达。
Mol Microbiol. 2007 Oct;66(1):110-26. doi: 10.1111/j.1365-2958.2007.05900.x. Epub 2007 Aug 28.
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Isolation and characterization of a new plasmid pSpnP1 from a multidrug-resistant clone of Streptococcus pneumoniae.从肺炎链球菌多重耐药克隆中分离并鉴定新型质粒pSpnP1
Plasmid. 2007 Jul;58(1):51-60. doi: 10.1016/j.plasmid.2006.12.006. Epub 2007 Feb 2.
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Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network.由肺炎球菌分子流行病学网络定义的肺炎链球菌主要耐药克隆的命名法。
J Clin Microbiol. 2001 Jul;39(7):2565-71. doi: 10.1128/JCM.39.7.2565-2571.2001.
6
Mosaic genes and mosaic chromosomes: intra- and interspecies genomic variation of Streptococcus pneumoniae.镶嵌基因与镶嵌染色体:肺炎链球菌的种内和种间基因组变异
Infect Immun. 2001 Apr;69(4):2477-86. doi: 10.1128/IAI.69.4.2477-2486.2001.
7
Extensive variation in the ddl gene of penicillin-resistant Streptococcus pneumoniae results from a hitchhiking effect driven by the penicillin-binding protein 2b gene.耐青霉素肺炎链球菌ddl基因的广泛变异是由青霉素结合蛋白2b基因驱动的搭便车效应所致。
Mol Biol Evol. 1999 Dec;16(12):1687-95. doi: 10.1093/oxfordjournals.molbev.a026082.
8
Epidemiological studies on drug resistance in Streptococcus pneumoniae in Hungary: an update for the 1990s.
Microb Drug Resist. 1999 Fall;5(3):201-5. doi: 10.1089/mdr.1999.5.201.
9
Penicillin-binding proteins as resistance determinants in clinical isolates of Streptococcus pneumoniae.肺炎链球菌临床分离株中作为耐药决定因素的青霉素结合蛋白
Microb Drug Resist. 1996 Summer;2(2):177-81. doi: 10.1089/mdr.1996.2.177.
10
Novel penicillin-resistant clones of Streptococcus pneumoniae in the Czech Republic and in Slovakia.捷克共和国和斯洛伐克出现的新型耐青霉素肺炎链球菌克隆株。
Microb Drug Resist. 1995 Spring;1(1):71-8. doi: 10.1089/mdr.1995.1.71.

来自匈牙利的两株血清型19A序列型226临床分离株的基因组序列草图,Hu17具有高水平β-内酰胺抗性,Hu15为青霉素敏感表型。

Draft Genome Sequences of Two Serotype 19A Sequence Type 226 Clinical Isolates from Hungary, Hu17 with High-Level Beta-Lactam Resistance and Hu15 of a Penicillin-Sensitive Phenotype.

作者信息

Rieger Martin, Denapaite Dalia, Brückner Reinhold, Maurer Patrick, Hakenbeck Regine

机构信息

Department of Microbiology, University of Kaiserslautern, Kaiserslautern, Germany.

Department of Microbiology, University of Kaiserslautern, Kaiserslautern, Germany

出版信息

Genome Announc. 2017 May 18;5(20):e00401-17. doi: 10.1128/genomeA.00401-17.

DOI:10.1128/genomeA.00401-17
PMID:28522729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5442385/
Abstract

The draft genome sequences of two multiple-antibiotic-resistant isolates from Hungary, Hu15 and Hu17, are reported here. Strain Hu15 is penicillin susceptible, whereas Hu17 is a high-level-penicillin-resistant strain. Both isolates belong to the serotype 19A sequence type 226, a single-locus variant (in the locus) of the Hungary-6 clone.

摘要

本文报道了从匈牙利分离出的两株多重耐药菌株Hu15和Hu17的基因组序列草图。菌株Hu15对青霉素敏感,而Hu17是一株高水平耐青霉素菌株。这两株分离株均属于血清型19A序列类型226,是匈牙利-6克隆的一个单基因座变体(在该基因座中)。