Maroof Syed Umair, Shaukat Faizan, Aslam Junaid, Jawaid Masood
Syed Umair Maroof, B-Pharm, MBA PharmEvo [Pvt] Limited, Karachi, Pakistan.
Dr. Faizan Shaukat, MBBS Senior Executive, Medical Affairs, PharmEvo [Pvt] Limited, Karachi, Pakistan.
Pak J Med Sci. 2017 Mar-Apr;33(2):498-501. doi: 10.12669/pjms.332.12454.
To ascertain patients and physician views regarding hazard and compliance of oral liquid Vitamin D glass ampoule and tablets.
This cross sectional survey was conducted from November 1 2016 to 15 December 2016. Patients who were prescribed Vitamin D glass ampoule from oral route in last three months were included along with physicians who routinely prescribe vitamin D after taking informed consent. The participants were asked about injuries related to the use of glass ampoule, ease of using this from, after taste preference of tablet or injectable form as well as demography. Data was analysed with SPSS version 24.0.
Total 182 patients were included in the study with mean ± SD age of 39.4 ± 12.4 years. Majority of patients, 80.2% (142) said they prefer oral tablet in preference to injectable ampule in oral form if given choice while prescribing Vitamin D. Moreover 66.7% (64) doctors prefer to prescribe tablet form of Vitamin D instead of injection as oral form for vitamin D deficiency among their patients. One third of patients, 33% (n=59) sustained injury while breaking the ampule which included minor self-controlled bleeding by glass particles in 50% (n=35). Less than half of doctors 46.9% (n=45) said they taught their patients about usage of injectable Vitamin D ampules.
Majority of patients prefer Vitamin D tablet instead of Oral liquid in glass ampoule if they got the choice among two. The results of this study provide important implications for our doctors about patients concern of hazard, after taste and compliance with orally administered Vitamin D glass ampoules.
确定患者和医生对口服液体维生素D玻璃安瓿剂和片剂的风险及依从性的看法。
本横断面调查于2016年11月1日至2016年12月15日进行。纳入过去三个月内接受过口服维生素D玻璃安瓿剂治疗的患者，以及在获得知情同意后常规开具维生素D处方的医生。参与者被问及与使用玻璃安瓿剂相关的损伤、使用的便利性、片剂或注射剂的口味偏好以及人口统计学信息。数据采用SPSS 24.0版进行分析。
共有182名患者纳入研究，平均年龄±标准差为39.4±12.4岁。大多数患者，80.2%（142名）表示，如果在开具维生素D处方时有选择，他们更喜欢口服片剂而非口服注射用安瓿剂。此外，66.7%（64名）的医生在为患者治疗维生素D缺乏症时，更喜欢开具维生素D片剂而非注射剂作为口服剂型。三分之一的患者，33%（n=59）在打破安瓿时受伤，其中50%（n=35）为玻璃颗粒导致的轻微自控出血。不到一半的医生，46.9%（n=45）表示他们会向患者传授注射用维生素D安瓿剂的使用方法。
如果可以在两者之间选择，大多数患者更喜欢维生素D片剂而非玻璃安瓿剂中的口服液体剂型。本研究结果为医生提供了重要启示，让他们了解患者对口服维生素D玻璃安瓿剂的风险、口味和依从性的担忧。
