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Free Bone Grafts for Mandibular Reconstruction in Patients Who Have Not Received Radiotherapy: The 6-cm Rule-Myth or Reality?未接受放疗患者下颌骨重建的游离骨移植:6厘米规则——神话还是现实?
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本文引用的文献

1
Nonvascularized bone grafts for segmental reconstruction of the mandible--a reappraisal.用于下颌骨节段性重建的非血管化骨移植——重新评估
J Oral Maxillofac Surg. 2009 Jul;67(7):1446-52. doi: 10.1016/j.joms.2008.12.052.
2
Mandibular reconstruction in adults: a review.成人下颌骨重建:综述
Int J Oral Maxillofac Surg. 2008 Jul;37(7):597-605. doi: 10.1016/j.ijom.2008.03.002. Epub 2008 May 1.
3
Comparison of the late results of mandibular reconstruction using nonvascularized or vascularized grafts and dental implants.使用非血管化或血管化移植物及牙种植体进行下颌骨重建的远期结果比较。
J Oral Maxillofac Surg. 1999 Aug;57(8):944-50; discussion 950-1. doi: 10.1016/s0278-2391(99)90015-0.
4
Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bony union and endosseous implant success.用于下颌骨重建的带血管蒂骨瓣与非带血管蒂骨移植:一期骨愈合和骨内种植体成功率的结果分析
Head Neck. 1999 Jan;21(1):66-71. doi: 10.1002/(sici)1097-0347(199901)21:1<66::aid-hed9>3.0.co;2-z.
5
A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects.血管化与非血管化骨移植重建下颌骨连续性缺损的比较。
J Oral Maxillofac Surg. 1997 Nov;55(11):1200-6. doi: 10.1016/s0278-2391(97)90165-8.

未接受放疗患者下颌骨重建的游离骨移植:6厘米规则——神话还是现实?

Free Bone Grafts for Mandibular Reconstruction in Patients Who Have Not Received Radiotherapy: The 6-cm Rule-Myth or Reality?

作者信息

Nandra Baljeet, Fattahi Tirbod, Martin Tim, Praveen Prav, Fernandes Rui, Parmar Sat

机构信息

Department of Oral and Maxillofacial Surgery, University Hospital Birmingham, England, United Kingdom.

Department of Oral and Maxillofacial Surgery, University of Florida, Jacksonville, Florida.

出版信息

Craniomaxillofac Trauma Reconstr. 2017 Jun;10(2):117-122. doi: 10.1055/s-0036-1597583. Epub 2017 Feb 7.

DOI:10.1055/s-0036-1597583
PMID:28523085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5435492/
Abstract

Bony reconstruction of the mandible after surgical resection results in improved rehabilitation and aesthetics. Composite tissue transfer has transformed reconstruction, particularly in patients who have received radiotherapy. However, there is morbidity related to free tissue transfer. Free nonvascularized bone grafts have much lower morbidity. Surgeons believe that free bone grafts greater than 6.0 cm are prone to failure. The aims of this study was to assess whether bone grafts greater than 6.0 cm in length have a high risk of failure. A retrospective study was performed on all patients who had free bone grafts greater than 6.0 cm in length at Birmingham, UK, and Florida, the United States. None of the patients received radiotherapy. A total of 14 patients had undergone bone grafts for mandibular defects greater than 6.0 cm in length; 13 of the bone grafts were successful. Of these 13, none were infected and there was radiographic evidence of bony union. Some of the patients have been dentally rehabilitated with implants. Contrary to much of the literature and many surgeons belief, our study has shown that long mandibular defects (>6.0 cm) are not a contraindication to the use of free bone grafts. Key principles to achieve success are discussed in this article.

摘要

手术切除后下颌骨的骨重建可改善康复效果和美观度。复合组织移植改变了重建方式,尤其是在接受过放疗的患者中。然而,游离组织移植存在相关并发症。游离非血管化骨移植的并发症要低得多。外科医生认为,长度大于6.0厘米的游离骨移植易于失败。本研究的目的是评估长度大于6.0厘米的骨移植是否具有较高的失败风险。对英国伯明翰和美国佛罗里达州所有接受过长度大于6.0厘米游离骨移植的患者进行了一项回顾性研究。所有患者均未接受放疗。共有14例患者接受了长度大于6.0厘米的下颌骨缺损骨移植;其中13例骨移植成功。在这13例中,无一例感染,且有影像学证据显示骨愈合。部分患者已通过植入物进行了牙齿修复。与许多文献及众多外科医生的观点相反,我们的研究表明,长节段下颌骨缺损(>6.0厘米)并非游离骨移植的禁忌证。本文讨论了取得成功的关键原则。