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伯基特淋巴瘤作为一名人类免疫缺陷病毒患者空肠空肠套叠的起始点。

Burkitt lymphoma as a lead point for jejunojejunal intussusception in a human immunodeficiency virus patient.

作者信息

Sharma Prabin, Balasingham Shivashanker, Stawiarski Kristin, Rahmani Mahboubeh, Costantino Antonio, Sharma Pranav, Xu Mina, Masoud Amir

机构信息

Department of Internal Medicine, Yale New Haven Health, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT, 06610, USA.

Department of Pathology, Yale New Haven Hospital, 310 Cedar Street LH 108, New Haven, CT, 06520, USA.

出版信息

Clin J Gastroenterol. 2017 Aug;10(4):342-350. doi: 10.1007/s12328-017-0747-y. Epub 2017 May 18.

Abstract

Intussusception is commonly seen in children but is rare in adults and represents only 5% of all intussusceptions causing 1% of intestinal obstructions. More than 50% of these intussusceptions in adults are due to intestinal neoplasms, including malignant lymphoma, e.g., Burkitt lymphoma. These lymphomas are more common in human immunodeficiency virus (HIV)-positive patients than in the general population. We present a case of a young male who was diagnosed with HIV when he developed intestinal obstruction and intussusception secondary to Burkitt lymphoma. He was managed with surgical resection followed by chemotherapy and antiretroviral treatment. HIV patients presenting with acute abdomen pose a diagnostic challenge to clinicians due to a wide range of differential diagnoses including inflammatory, infectious and neoplastic conditions. In a young HIV patient presenting with acute abdomen, intussusception caused by Burkitt lymphoma should be considered in the differential.

摘要

肠套叠在儿童中常见,但在成人中罕见,仅占所有肠套叠的5%,导致肠梗阻的1%。成人中超过50%的此类肠套叠是由肠道肿瘤引起的,包括恶性淋巴瘤,如伯基特淋巴瘤。这些淋巴瘤在人类免疫缺陷病毒(HIV)阳性患者中比在普通人群中更常见。我们报告一例年轻男性病例,他在因伯基特淋巴瘤出现肠梗阻和肠套叠时被诊断出感染HIV。他接受了手术切除,随后进行化疗和抗逆转录病毒治疗。由于包括炎症、感染和肿瘤性疾病在内的多种鉴别诊断,出现急腹症的HIV患者给临床医生带来了诊断挑战。在一名出现急腹症的年轻HIV患者中,鉴别诊断应考虑伯基特淋巴瘤引起的肠套叠。

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