Jackson Robert T
Department of Human Nutrition and Food Systems, University of Maryland, College Park, Maryland 20742.
Am J Hum Biol. 1992;4(3):313-318. doi: 10.1002/ajhb.1310040306.
There are conflicting reports about the nature and magnitude of hemoglobin (Hb) differences between African Americans (AA) and European Americans (EA). Several reports suggest that AA have lower mean Hb values and that differences between AA and EA are large and are due to "racial" differences. Some have even called for separate Hb standards. In this study, Hb comparisons were made between AA and EA males in the Second National Health and Nutrition Examination Survey, 1976-1980. Comparison of AA and EA males with normal Hb values (i.e., 13.0 g/dl or greater) indicated that observed mean Hb differences exist primarily at the lower end of the Hb distribution (i.e., the distribution is skewed to the left). Several factors are likely contributors to lower hemoglobin values at the lower end of the distribution, including hemoglobinopathies, thalassemias, and/or nutritional deficiencies. If racial differences exist between these groups, controlled prospective studies are necessary to demonstrate this possibility. This study supports a single Hb standard for AA and EA males. © 1992 Wiley-Liss, Inc.
关于非裔美国人（AA）和欧裔美国人（EA）之间血红蛋白（Hb）差异的性质和程度，存在相互矛盾的报道。一些报道表明，非裔美国人的平均Hb值较低，且非裔美国人和欧裔美国人之间的差异很大，是由“种族”差异导致的。有些人甚至呼吁制定单独的Hb标准。在这项研究中，对1976 - 1980年第二次全国健康与营养检查调查中的非裔美国人和欧裔美国男性进行了Hb比较。对具有正常Hb值（即13.0克/分升或更高）的非裔美国人和欧裔美国男性进行比较表明，观察到的平均Hb差异主要存在于Hb分布的低端（即分布向左偏斜）。分布低端血红蛋白值较低可能有几个因素，包括血红蛋白病、地中海贫血和/或营养缺乏。如果这些群体之间存在种族差异，需要进行对照前瞻性研究来证明这种可能性。本研究支持为非裔美国人和欧裔美国男性制定单一的Hb标准。© 1992威利 - 利斯公司。
