糖尿病患者迷走神经的诊断性超声检查
Diagnostic Ultrasound of the Vagus Nerve in Patients with Diabetes.
作者信息
Tawfik Eman A, Walker Francis O, Cartwright Michael S, El-Hilaly Rana A
机构信息
Department of Physical Medicine & Rehabilitation, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Department of Neurology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC.
出版信息
J Neuroimaging. 2017 Nov;27(6):589-593. doi: 10.1111/jon.12452. Epub 2017 May 19.
BACKGROUND AND PURPOSE
Autonomic neuropathy is a serious and common complication of diabetes mellitus. The vagus nerve is the longest autonomic nerve, and may be affected in diabetes as a part of generalized neuropathy. Our objective was to assess for possible sonographic changes of the vagus nerve in diabetic patients.
METHODS
The vagus nerve was bilaterally scanned in 20 healthy volunteers and 54 patients with diabetes in the axial plane at the lateral neck.
RESULTS
The mean cross-sectional area of the vagus nerve was significantly smaller in patients with diabetes compared with controls. Receiver operating characteristic curve analyses revealed an area under the curve of .96, and an optimum cutoff point of 3 mm with a sensitivity of 85.2% and specificity of 100%.
CONCLUSIONS
This study demonstrates a degree of vagus nerve atrophy in patients with diabetes. This finding may have relevance in the diagnosis and treatment of diabetic neuropathy if further validated.
背景与目的
自主神经病变是糖尿病严重且常见的并发症。迷走神经是最长的自主神经，作为广泛性神经病变的一部分，在糖尿病中可能会受到影响。我们的目的是评估糖尿病患者迷走神经可能存在的超声变化。
方法
对20名健康志愿者和54名糖尿病患者的迷走神经在颈部外侧的轴平面进行双侧扫描。
结果
与对照组相比，糖尿病患者迷走神经的平均横截面积显著更小。受试者操作特征曲线分析显示曲线下面积为0.96，最佳截断点为3mm，敏感性为85.2%，特异性为100%。
结论
本研究证明糖尿病患者存在一定程度的迷走神经萎缩。如果进一步得到验证，这一发现可能与糖尿病神经病变的诊断和治疗相关。
Zotero 插件