Department of Neurosurgery, Kumamoto University Medical School, Kumamoto, Japan
J Neurosurg. 2018 Mar;128(3):862-866. doi: 10.3171/2016.12.JNS161820. Epub 2017 May 19.
Improvement of visual field defects after surgical treatment for occipital lobe epilepsy is rare. Here, the authors report on a 24-year-old man with a 15-year history of refractory epilepsy that developed after he had undergone an occipital craniotomy to remove a cerebellar astrocytoma at the age of 4. His seizures started with an elementary visual aura, followed by secondary generalized tonic-clonic convulsion. Perimetry revealed left-sided incomplete hemianopia, and MRI showed an old contusion in the right occipital lobe. After evaluation with ictal video-electroencephalography, electrocorticography, and mapping of the visual cortex with subdural electrodes, the patient underwent resection of the scarred tissue, including the epileptic focus at the occipital lobe. After surgery, he became seizure free and his visual field defect improved gradually. In addition, postoperative I-iomazenil (IMZ) SPECT showed partly normalized IMZ uptake in the visual cortex. This case is a practical example suggesting that neurological deficits attributable to the functional deficit zone can be remedied by successful focal resection.
术后视野缺损改善的枕叶癫痫很少见。作者报告了 1 例 24 岁男性,15 年前因小脑星形细胞瘤行枕骨开颅术,术后出现难治性癫痫。他的癫痫发作始于初级视觉先兆,继之以全面强直阵挛性癫痫发作。视野检查显示左侧不完全偏盲,MRI 显示右侧枕叶陈旧性挫伤。进行发作期视频-脑电图、皮质电图和硬膜下电极视觉皮质定位评估后,患者行瘢痕组织切除术,包括枕叶癫痫灶。术后患者无癫痫发作,视野缺损逐渐改善。此外,术后 I-iomazenil(IMZ)SPECT 显示视觉皮质的 IMZ 摄取部分正常化。这个病例是一个实际的例子,表明由于功能缺陷区导致的神经功能缺损可以通过成功的病灶切除得到纠正。