Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Department of Neurosurgery, New York University Grossman School of Medicine, New York City, NYC, USA.
Neurosurg Rev. 2024 Aug 30;47(1):514. doi: 10.1007/s10143-024-02772-8.
Occipital lobe epilepsy (OLE) is an uncommon type of extratemporal epilepsy constituting roughly 2-13% of symptomatic partial epilepsies and epilepsy surgery cases. Over two-thirds of patients with OLE present with two characteristics: (1) ictal semiology compatible with an occipital seizure focus (e.g., ictal blindness, visual perceptual disturbance, eye blinking, nystagmus), and (2) lateralizing features referable to the posterior cortex (e.g., visual field defects, contralateral head deviation). The remaining one-third of patients present with ≥ 2 seizure types, indicative of spread to other lobes. A common representation of this cortical spread is the altered mental status and generalized tonic-clonic activity seen in patient with OLE. While the key clinical symptoms include visual hallucinations, it may be difficult to elicit on history, especially from children, and are not always present.
枕叶癫痫(OLE)是一种罕见的颞外癫痫类型,约占症状性部分性癫痫和癫痫手术病例的 2-13%。超过三分之二的 OLE 患者具有以下两个特征:(1)发作时表现与枕叶癫痫灶一致(例如,发作性失明、视觉感知障碍、眨眼、眼球震颤);(2)与后皮质相关的定位特征(例如,视野缺损、对侧头部偏斜)。其余三分之一的患者表现出≥2 种发作类型,提示病变已扩散至其他脑叶。这种皮质扩散的一个常见表现是 OLE 患者出现的意识状态改变和全面强直阵挛发作。虽然主要的临床症状包括视觉幻觉,但病史中可能难以引出,尤其是儿童,而且并不总是存在。