From the Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.
Clin Nucl Med. 2017 Jul;42(7):532-533. doi: 10.1097/RLU.0000000000001700.
Ga-PSMA PET/CT is currently used for detection of prostate cancer including metastases, even at low prostate-specific antigen values. A grown number of reports have shown increased uptake of PSMA in neovessels of nonprostatic malignancies including lung cancer, and recently a case report has demonstrated increased PSMA uptake in colorectal adenocarcinoma. In this case report, we demonstrate increased Ga-PMSA uptake on PET/CT in metastases from previously treated colon adenocarcinoma, and it illustrates the importance of histology of suspicious lesions on Ga-PSMA PET/CT.
Ga-PSMA PET/CT 目前用于检测前列腺癌，包括转移灶，即使在前列腺特异性抗原值较低的情况下也是如此。越来越多的报告显示，非前列腺恶性肿瘤的新生血管对 PSMA 的摄取增加，包括肺癌，最近有一份病例报告显示结直肠腺癌的 PSMA 摄取增加。在本病例报告中，我们展示了先前治疗过的结肠腺癌转移灶中 Ga-PSMA PET/CT 摄取增加的情况，这说明了 Ga-PSMA PET/CT 上可疑病变的组织学的重要性。
