• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年患者麻醉药物的药理学考量

Pharmacologic Considerations of Anesthetic Agents in Geriatric Patients.

作者信息

Rana Maunak V, Bonasera Lara K, Bordelon Gregory J

机构信息

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, 836 West Wellington Avenue, #4815, Chicago, IL 60657, USA.

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, 836 West Wellington Avenue, #4815, Chicago, IL 60657, USA.

出版信息

Anesthesiol Clin. 2017 Jun;35(2):259-271. doi: 10.1016/j.anclin.2017.01.011. Epub 2017 Mar 30.

DOI:10.1016/j.anclin.2017.01.011
PMID:28526147
Abstract

Aging is a natural process of declining organ function and reserve. Census data show that the geriatric population is expected to grow to nearly 30%. More than half of geriatric patients have 1 or more surgical procedures in their lifetimes. Moreover, this is the population at greatest risk of morbidity and mortality with any given complication. There is remarkable variability in health across the age spectrum, from fit to frail and compromised. This variability requires a unique approach to anesthetic delivery and drug dosing on an individual basis to avoid complications such as postoperative cognitive dysfunction and delirium.

摘要

衰老乃是器官功能与储备下降的自然过程。人口普查数据显示,老年人口预计将增长至近30%。超过半数的老年患者一生中会接受1次或更多次外科手术。此外,这一人群在出现任何特定并发症时发生发病和死亡的风险最高。从健康到体弱和功能受损,整个年龄范围内的健康状况存在显著差异。这种差异需要一种独特的个体化麻醉给药和药物剂量方法,以避免诸如术后认知功能障碍和谵妄等并发症。

相似文献

1
Pharmacologic Considerations of Anesthetic Agents in Geriatric Patients.老年患者麻醉药物的药理学考量
Anesthesiol Clin. 2017 Jun;35(2):259-271. doi: 10.1016/j.anclin.2017.01.011. Epub 2017 Mar 30.
2
Special Considerations for the Aging Brain and Perioperative Neurocognitive Dysfunction.衰老大脑与围手术期神经认知功能障碍的特殊考量
Anesthesiol Clin. 2019 Sep;37(3):521-536. doi: 10.1016/j.anclin.2019.04.010. Epub 2019 Jun 17.
3
Postoperative confusion in older adults.老年人术后认知功能障碍
JAAPA. 2017 Apr;30(4):12-16. doi: 10.1097/01.JAA.0000513345.29384.39.
4
Cognitive function after anaesthesia in the elderly.老年人麻醉后的认知功能。
Best Pract Res Clin Anaesthesiol. 2003 Jun;17(2):259-72. doi: 10.1016/s1521-6896(03)00005-3.
5
Pharmacological considerations in the elderly.老年人的药理学考量
Curr Opin Anaesthesiol. 2018 Feb;31(1):11-18. doi: 10.1097/ACO.0000000000000544.
6
Anesthesia for breast cancer surgery in the elderly.老年乳腺癌手术的麻醉
Crit Rev Oncol Hematol. 2003 May;46(2):115-20. doi: 10.1016/s1040-8428(02)00122-1.
7
[Anesthesia for thoracic surgery in elderly patients].老年患者胸外科手术的麻醉
Kyobu Geka. 2005 Jul;58(8 Suppl):607-12.
8
Should general anaesthesia be avoided in the elderly?老年人是否应该避免全身麻醉?
Anaesthesia. 2014 Jan;69 Suppl 1(Suppl 1):35-44. doi: 10.1111/anae.12493.
9
[Postoperative cognitive dysfunction of older surgical patients].老年外科手术患者的术后认知功能障碍
Medicina (Kaunas). 2010;46(3):169-75.
10
Postoperative delirium - treatment and prevention.术后谵妄——治疗和预防。
Curr Opin Anaesthesiol. 2021 Feb 1;34(1):27-32. doi: 10.1097/ACO.0000000000000939.

引用本文的文献

1
Safety of geriatric patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration with deep sedation: a retrospective study.老年患者在深度镇静下接受支气管内超声引导经支气管针吸活检的安全性:一项回顾性研究。
BMC Anesthesiol. 2023 Aug 16;23(1):276. doi: 10.1186/s12871-023-02241-7.
2
NEW CONCEPT OF FUSION TECHNICS IN REGIONAL ANESTHESIA.区域麻醉中融合技术的新概念。
Acta Clin Croat. 2022 Sep;61(Suppl 2):135-144. doi: 10.20471/acc.2022.61.s2.18.
3
Population pharmacokinetic and pharmacodynamic model of propofol externally validated in Korean elderly subjects.
丙泊酚群体药代动力学和药效学模型在韩国老年受试者中的外部验证
J Pharmacokinet Pharmacodyn. 2023 Apr;50(2):97-109. doi: 10.1007/s10928-022-09836-6. Epub 2022 Dec 16.
4
Prehabilitation of elderly frail or pre-frail patients prior to elective surgery (PRAEP-GO): study protocol for a randomized, controlled, outcome assessor-blinded trial.择期手术前老年虚弱或衰弱前期患者的预康复(PRAEP-GO):一项随机、对照、结局评估者盲法试验的研究方案。
Trials. 2022 Jun 6;23(1):468. doi: 10.1186/s13063-022-06401-x.
5
Frailty and anesthesia - risks during and post-surgery.衰弱与麻醉——手术期间及术后的风险
Local Reg Anesth. 2018 Oct 5;11:61-73. doi: 10.2147/LRA.S142996. eCollection 2018.
6
Geriatric Anesthesia-related Morbidity and Mortality in China: Current Status and Trend.中国老年患者麻醉相关发病率和死亡率:现状和趋势。
Chin Med J (Engl). 2017 Nov 20;130(22):2738-2749. doi: 10.4103/0366-6999.218006.