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减重手术对勃起功能的影响如何?系统评价和荟萃分析。

What Is the Impact of Bariatric Surgery on Erectile Function? A Systematic Review and Meta-Analysis.

机构信息

Faculdade de Ciências Médicas de Santos, Centro Universitário Lusíada, São Paulo, Brazil.

Department of Urology, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil.

出版信息

Sex Med Rev. 2017 Jul;5(3):393-402. doi: 10.1016/j.sxmr.2017.03.008. Epub 2017 May 16.

DOI:10.1016/j.sxmr.2017.03.008
PMID:28526630
Abstract

INTRODUCTION

Obesity is a worldwide public health issue that has severe psychological and social implications. Erectile dysfunction also is a prevalent clinical situation, and obesity is one of the primary risk factors for its development.

AIM

To determine whether bariatric surgery can lessen erectile dysfunction in obese men because of evidence showing that weight loss in obese men contributes to decreasing erectile dysfunction and bariatric surgery contributes to significant weight loss.

METHODS

A search was conducted using Medline, LILACS, Cochrane, Scopus, CINAHL, Embase, Web of Science, Eric, and EBM up to April 13, 2016. The authors selected by title, abstract, and full text. Scottish Intercollegiate Guidelines Network checklists were used for comparative studies to show the limitations and biases of each article. RevMan 5.3 software from the Cochrane Library was used for meta-analyses. Results were demonstrated with forest plots.

MAIN OUTCOME MEASURES

The outcome selected was resolution of erectile dysfunction, which was analyzed by improvement in the International Index of Erectile Function (IIEF) score.

RESULTS

Of 185 articles analyzed, 7 were selected for systematic review. Meta-analysis of two articles that evaluated erectile function showed a 5.66-point increase in the five-item IIEF score of patients who underwent bariatric surgery (95% CI = 7.88-3.45, I = 35%, P < .00001), demonstrating statistical significance. Meta-analysis of three articles showed a 4.10-point increase in the IIEF erectile function score of patients who underwent bariatric surgery (95% CI = 6.10-2.10, I = 0%, P < .0001), demonstrating statistical significance.

CONCLUSION

Bariatric surgery leads to an improvement of erectile function. Glina FPI, de Freitas Barboza JW, Nunes VM, et al. What Is the Impact of Bariatric Surgery on Erectile Function? A Systematic Review and Meta-Analysis. Sex Med Rev 2017;5:393-402.

摘要

简介

肥胖是一个全球性的公共卫生问题,它会对人们的心理和社交产生严重影响。勃起功能障碍也是一种普遍的临床情况,肥胖是其发展的主要危险因素之一。

目的

确定减重手术是否可以减轻肥胖男性的勃起功能障碍,因为有证据表明肥胖男性的体重减轻有助于减少勃起功能障碍,而减重手术有助于显著减轻体重。

方法

使用 Medline、LILACS、Cochrane、Scopus、CINAHL、Embase、Web of Science、Eric 和 EBM 数据库进行搜索,检索日期截至 2016 年 4 月 13 日。通过标题、摘要和全文选择作者。苏格兰校际指南网络清单被用于比较研究,以显示每篇文章的局限性和偏见。Cochrane 图书馆的 RevMan 5.3 软件用于荟萃分析。结果用森林图表示。

主要观察指标

选择的结果是勃起功能障碍的解决情况,通过国际勃起功能指数(IIEF)评分的改善来分析。

结果

在分析的 185 篇文章中,有 7 篇被选为系统综述。对评估勃起功能的两篇文章进行荟萃分析显示,接受减重手术的患者的五项 IIEF 评分增加了 5.66 分(95%CI=7.88-3.45,I=35%,P<.00001),具有统计学意义。对三篇文章进行荟萃分析显示,接受减重手术的患者的 IIEF 勃起功能评分增加了 4.10 分(95%CI=6.10-2.10,I=0%,P<.0001),具有统计学意义。

结论

减重手术可改善勃起功能。Glina FPI、de Freitas Barboza JW、Nunes VM 等人。减重手术对勃起功能有何影响?系统评价和荟萃分析。性医学评论 2017;5:393-402。

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