臭氧与光生物调节疗法对大鼠颏神经损伤的比较
Comparison of Ozone and Photo-Biomodulation Therapies on Mental Nerve Injury in Rats.
作者信息
Yucesoy Turker, Kutuk Nukhet, Canpolat Dilek Gunay, Alkan Alper
机构信息
Doctor, Oral and Maxillofacial Surgery Department, Dentistry Faculty, Bezmialem Vakif University, Istanbul, Turkey.
Associate Professor, Oral and Maxillofacial Surgery Department, Dentistry Faculty, Erciyes University, Kayseri, Turkey.
出版信息
J Oral Maxillofac Surg. 2017 Nov;75(11):2323-2332. doi: 10.1016/j.joms.2017.04.016. Epub 2017 Apr 26.
PURPOSE
This study compared photo-biomodulation (PBM) and ozone therapy (OT) for mental nerve injury by counting Schwann cells (SCs) and fasciculated nerve branches and measuring fascicular nerve areas.
MATERIALS AND METHODS
The effects of OT and PBM on mental nerve injury were evaluated. Mental nerves of 27 rats were partly sutured and allocated into 3 groups. Group 1 received no treatment, group 2 received OT, and group 3 received PBM. The number of fascicules beyond nerve branches and the number of SCs before and after nerve injury were evaluated histologically.
RESULTS
A better healing pattern was observed in the treatment groups. The number of SCs was markedly larger in the OT and PBM groups than in the control group.
CONCLUSIONS
Oral and maxillofacial surgeons should be familiar with the differential diagnosis, prevention, and management of neurosensory disturbances. This study provides insights into the management of neurosensory disturbances related to mental nerve injury using OT and PBM. This study clearly suggests that OT and PBM are promising novel methods for the treatment of mental nerve injury.
目的
本研究通过计数施万细胞（SCs）和有束状神经分支以及测量束状神经面积，比较光生物调节（PBM）和臭氧疗法（OT）对颏神经损伤的影响。
材料与方法
评估OT和PBM对颏神经损伤的影响。将27只大鼠的颏神经部分缝合，并分为3组。第1组不接受治疗，第2组接受OT，第3组接受PBM。通过组织学评估神经分支外的束状数量以及神经损伤前后SCs的数量。
结果
在治疗组中观察到更好的愈合模式。OT组和PBM组中的SCs数量明显多于对照组。
结论
口腔颌面外科医生应熟悉神经感觉障碍的鉴别诊断、预防和处理。本研究为使用OT和PBM处理与颏神经损伤相关的神经感觉障碍提供了见解。本研究明确表明，OT和PBM是治疗颏神经损伤的有前景的新方法。
Zotero 插件