Shimizu Kenta, Isozumi Rie, Takami Kazutoshi, Kimata Isao, Shiokawa Kanae, Yoshimatsu Kumiko, Tsuda Yoshimi, Nishio Sanae, Arikawa Jiro
Department of Microbiology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan.
Department of Parasitology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
J Vet Med Sci. 2017 Jul 19;79(7):1261-1263. doi: 10.1292/jvms.17-0067. Epub 2017 May 22.
We examined 33 rodents captured in an urban area of Osaka City, Japan for IgG antibodies against Seoul virus, severe fever with thrombocytopenia syndrome virus, hepatitis E virus, Leptospira interrogans, Yersinia pestis, spotted fever, typhus and scrub typhus group rickettsiae. We found that 3 (9.1%) and 1 (3.0%) of the 33 rodents had antibodies against L. interrogans and spotted fever group rickettsiae, respectively. DNAs of leptospires were detected from 2 of the 3 seropositive rodents, but DNA of rickettsia was not detected. Phylogenetic analysis and multiple locus sequence typing revealed that the 2 leptospires were L. interrogans belonging to a novel sequence type. There is a potential risk for acquiring rodent-borne zoonotic pathogens even in cities in developed countries.
我们对在日本大阪市市区捕获的33只啮齿动物进行了检测，以检测其针对汉城病毒、严重发热伴血小板减少综合征病毒、戊型肝炎病毒、问号钩端螺旋体、鼠疫耶尔森菌、斑点热、斑疹伤寒和恙虫病群立克次体的IgG抗体。我们发现，33只啮齿动物中有3只（9.1%）和1只（3.0%）分别具有针对问号钩端螺旋体和斑点热群立克次体的抗体。在3只血清阳性的啮齿动物中，有2只检测到钩端螺旋体的DNA，但未检测到立克次体的DNA。系统发育分析和多位点序列分型显示，这2株钩端螺旋体属于一种新型序列型的问号钩端螺旋体。即使在发达国家的城市，也存在感染啮齿动物传播的人畜共患病原体的潜在风险。
