Kaasa S, Mastekaasa A
Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway.
Acta Oncol. 1988;27(6b):829-35. doi: 10.3109/02841868809094368.
Patients with inoperable non-small cell lung cancer, limited disease, were randomized to either chemotherapy (cisplatin and etoposide) or radiotherapy of the thorax. A set of questionnaires, covering 4 areas: psychosocial well-being, medical side effects, physical function, and everyday activity was filled out by 101 patients. The correlations between psychosocial well-being (dependent variable) on the one hand, and medical side effects, physical function, and everyday activity (independent variables) on the other were subjected to multiple regression analysis. No significant correlation was found between psychosocial well-being and chemotherapy- or radiotherapy-related subjective side effects. The disease-related symptoms correlated highly with psychosocial well-being during the observation period. Psychosocial well-being and the independent variables tended to be more strongly correlated during the follow-up period (14-52 weeks) than during the treatment period.
患有无法手术的局限性非小细胞肺癌的患者被随机分为化疗组（顺铂和依托泊苷）或胸部放疗组。101名患者填写了一组涵盖4个领域的问卷：心理社会幸福感、医学副作用、身体功能和日常活动。对心理社会幸福感（因变量）与医学副作用、身体功能和日常活动（自变量）之间的相关性进行了多元回归分析。未发现心理社会幸福感与化疗或放疗相关的主观副作用之间存在显著相关性。在观察期内，疾病相关症状与心理社会幸福感高度相关。在随访期（14 - 52周），心理社会幸福感与自变量之间的相关性往往比治疗期更强。
