Kaasa S, Mastekaasa A, Naess S
Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.
Acta Oncol. 1988;27(4):335-42. doi: 10.3109/02841868809093551.
The quality of life of patients treated with radiotherapy and chemotherapy for non-small cell lung cancer is compared in a randomized study. A standardized questionnaire composed of 12 questions covering psychosocial well-being (10 question index), and global quality of life evaluation (2 questions) was used to evaluate the patient's quality of life. Data were collected before treatment was started and at 7 different occasions up to 52 weeks after the beginning of the first treatment. The psychosocial well-being index and the 2 global questions were found to have a high degree of validity in a previous study. Two weeks after the start of treatment, the psychosocial well-being index for patients receiving radiotherapy was significantly higher than for patients treated by cytostatic drugs. This observation was confirmed by the 2 global questions. No differences in the quality of life were detected in the follow-up period (6-52 weeks).
在一项随机研究中，对接受放疗和化疗的非小细胞肺癌患者的生活质量进行了比较。使用一份由12个问题组成的标准化问卷来评估患者的生活质量，这些问题涵盖心理社会幸福感（10个问题指标）和总体生活质量评估（2个问题）。在治疗开始前以及首次治疗开始后长达52周的7个不同时间点收集数据。在先前的一项研究中发现，心理社会幸福感指标和2个总体问题具有高度的有效性。治疗开始两周后，接受放疗的患者的心理社会幸福感指标显著高于接受细胞毒性药物治疗的患者。这一观察结果得到了2个总体问题的证实。在随访期（6 - 52周）未检测到生活质量的差异。
