Galvis Alvaro E, Kamboj Sana, Nakamura Craig
University of Nevada, School of Medicine, Department of Pediatrics, Lied Clinic, 1524 Pinto Lane, Second Floor, 89106 Las Vegas, NV, United States.
Children's Lung Specialist. 3820 Meadows Lane, Las Vegas Nevada 89107.
IDCases. 2017 Apr 26;9:9-11. doi: 10.1016/j.idcr.2017.04.014. eCollection 2017.
is the most common bacterial cause of community acquired pneumonia. The current trend in infections has been the rise of multi-drug resistance in the last two decades. We present the case of a pair of 16-month old African-American fraternal twins who presented to the emergency room on the same day for symptoms consistent with pneumonia. Upon further examination, the twins showed remarkably similar symptoms, and cultures revealed penicillin-resistant in both twins. The pneumonia affected both twins in the same way, but a tomography scan did not reveal any shared anatomical abnormalities to account for this near-identical progression. In a review of literature and case reports, there are no reported cases of fraternal twins with simultaneous or non-simultaneous pneumococcal pneumonia or effusions. This case suggests that there may be possible anatomical abnormalities in the fraternal twins which were not evident in routine testing that may have led to near-identical illnesses. The pathophysiology of the simultaneous and near identical infections is not clear but may reflect subtle genetic factors in the siblings.
是社区获得性肺炎最常见的细菌病因。在过去二十年中，感染的当前趋势是多重耐药性的上升。我们报告了一对16个月大的非裔美国异卵双胞胎的病例，他们在同一天因与肺炎相符的症状前往急诊室。进一步检查后，这对双胞胎表现出非常相似的症状，培养结果显示两人均对青霉素耐药。肺炎以相同方式影响了这对双胞胎，但断层扫描未发现任何共同的解剖学异常来解释这种几乎相同的病程。在对文献和病例报告的回顾中，没有关于异卵双胞胎同时或不同时发生肺炎球菌肺炎或胸腔积液的报道病例。该病例表明，异卵双胞胎可能存在常规检查中不明显的解剖学异常，这可能导致了几乎相同的疾病。同时发生且几乎相同感染的病理生理学尚不清楚，但可能反映了这对双胞胎中的细微遗传因素。
