类风湿关节炎中的葡萄糖代谢异常
Abnormal Glucose Metabolism in Rheumatoid Arthritis.
作者信息
Pi Hui, Zhou Haotong, Jin Huan, Ning Yaogui, Wang Youlian
机构信息
Department of Rheumatology, Jiangxi Provincial People's Hospital, Nanchang 330006, China.
Department of Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China.
出版信息
Biomed Res Int. 2017;2017:9670434. doi: 10.1155/2017/9670434. Epub 2017 Apr 26.
Abstract
The incidence of abnormal glucose metabolism in patients with rheumatoid arthritis was considerably higher than the general population. The persistent systemic inflammatory state in rheumatoid arthritis might be associated with the glucose metabolism dysfunction. In this context, insulin resistance, islet cell apoptosis, inflammatory cytokines, and other aspects which were linked with abnormal glucose metabolism in rheumatoid arthritis were reviewed. This review will be helpful in understanding the abnormal glucose metabolism mechanism in patients with rheumatoid arthritis and might be conducive to finding an effective treatment.
摘要
类风湿关节炎患者糖代谢异常的发生率显著高于普通人群。类风湿关节炎中持续的全身炎症状态可能与糖代谢功能障碍有关。在此背景下，对类风湿关节炎中与糖代谢异常相关的胰岛素抵抗、胰岛细胞凋亡、炎性细胞因子等方面进行了综述。本综述将有助于理解类风湿关节炎患者糖代谢异常的机制，并可能有助于找到有效的治疗方法。
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