Zhu Ziwen, Zhang Duo, Lee Heedoo, Jin Yang
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, Boston, USA.
Biomed Genet Genom. 2016 Jun;1(2):34-36. doi: 10.15761/BGG.1000106. Epub 2016 Jul 25.
(), a member of the phylum Nematoda, carries the evolutionarily conserved genes comparing to mammals. Due to its short lifespan and completely sequenced genome, becomes a potentially powerful model for mechanistic studies in human diseases. In this mini review, we will outline the current understandings on as a model organism for microRNA (miRNA)-related research in the pathogenesis of human diseases.
线虫门的成员（）与哺乳动物相比携带进化上保守的基因。由于其寿命短且基因组已完全测序，（）成为人类疾病机制研究的潜在强大模型。在本综述中，我们将概述关于（）作为人类疾病发病机制中与微小RNA（miRNA）相关研究的模式生物的当前认识。
