用于剖析微小RNA功能的重要工具。
: An important tool for dissecting microRNA functions.
作者信息
Zhu Ziwen, Zhang Duo, Lee Heedoo, Jin Yang
机构信息
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, Boston, USA.
出版信息
Biomed Genet Genom. 2016 Jun;1(2):34-36. doi: 10.15761/BGG.1000106. Epub 2016 Jul 25.
Abstract
(), a member of the phylum Nematoda, carries the evolutionarily conserved genes comparing to mammals. Due to its short lifespan and completely sequenced genome, becomes a potentially powerful model for mechanistic studies in human diseases. In this mini review, we will outline the current understandings on as a model organism for microRNA (miRNA)-related research in the pathogenesis of human diseases.
摘要
线虫门的成员（）与哺乳动物相比携带进化上保守的基因。由于其寿命短且基因组已完全测序，（）成为人类疾病机制研究的潜在强大模型。在本综述中，我们将概述关于（）作为人类疾病发病机制中与微小RNA（miRNA）相关研究的模式生物的当前认识。
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