Diamant Hagit, Okby Rania, Imterat Majdi, Sergienko Ruslan, Sheiner Eyal
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ben-Gurion University of the Negev, Epidemiology and Health Services Evaluation, Beer-Sheva, Israel.
Harefuah. 2016 Sep;155(9):547-550.
To investigate the rate, success and pregnancy outcome following a trial of labor after cesarean (TOLAC) in twin gestations. Study design: A retrospective study including all twin pregnancies with a single prior cesarean delivery between the years 2006 to 2011 was performed. Women with medical indications for cesarean delivery (CD) were excluded. Maternal and neonatal outcomes were compared between women who delivered by CD to those who underwent TOLAC. Stratified analysis using a multiple logistic regression model was performed to control for confounders.
During the years 2006-2011, 110 women met the inclusion criteria. Of these, 20% (n=22) underwent a TOLAC. The success rate of vaginal birth after cesarean was 77.2% (n=17). No cases of uterine rupture or dehiscence were noted. No significant difference was documented in neonatal outcome (including pH and Apgar scores) between the TOLAC and the CD group. Fertility treatment was noted as a risk factor for repeated CD (35.2 vs. 4.5%, OR=8.6, 95% CI 1.21-61.3, P=0.005). Using a multivariable analysis, with repeated CD as the outcome variable, controlling for confounders such as maternal age, and gestational age, fertility treatment was an independent risk factor for repeated CD (adjusted OR=5.2, 95% CI 0.01-0.70; P=0.02).
A TOLAC in twin gestation seems to be a safe option for the mother and newborn. Fertility treatment is an independent risk factor for repeated CD in twins.
探讨双胎妊娠剖宫产术后阴道试产(TOLAC)的发生率、成功率及妊娠结局。研究设计:进行一项回顾性研究,纳入2006年至2011年间有一次剖宫产史的所有双胎妊娠。有剖宫产医学指征的女性被排除。比较剖宫产分娩的女性与接受TOLAC的女性的母婴结局。采用多元逻辑回归模型进行分层分析以控制混杂因素。
2006 - 2011年期间,110名女性符合纳入标准。其中,20%(n = 22)接受了TOLAC。剖宫产术后阴道分娩成功率为77.2%(n = 17)。未发现子宫破裂或裂开病例。TOLAC组与剖宫产组在新生儿结局(包括pH值和阿氏评分)方面无显著差异。生育治疗被视为再次剖宫产的危险因素(35.2%对4.5%,OR = 8.6,95%CI 1.21 - 61.3,P = 0.005)。采用多变量分析,以再次剖宫产作为结局变量,控制产妇年龄和孕周等混杂因素,生育治疗是再次剖宫产的独立危险因素(调整后OR = 5.2,95%CI 0.01 - 0.70;P = 0.02)。
双胎妊娠的TOLAC对母亲和新生儿似乎是一种安全的选择。生育治疗是双胎再次剖宫产的独立危险因素。