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双胎经阴道分娩(TOLAC)是不良母婴结局的独立危险因素。

Twin TOLAC is an independent risk factor for adverse maternal and neonatal outcome.

机构信息

Department of Obstetrics and Gynecology, Mayanei Hayeshua Medical Center, 17 Harav Povarski Street, Bnei Bark, Israel.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Arch Gynecol Obstet. 2021 Dec;304(6):1433-1441. doi: 10.1007/s00404-021-06062-2. Epub 2021 Apr 20.

Abstract

PURPOSE

To determine factors associated with a successful twin trial of labor after Cesarean delivery (TOLAC).

METHODS

A retrospective cohort study was conducted at a single medical center in a population highly motivated for TOLAC (> 80%). The effect of maternal demographic and obstetric characteristics on the likelihood of twin TOLAC success was analyzed. Maternal complications and combined adverse outcome (uterine rupture, Apgar < 7 at 5 min, and umbilical cord pH < 7.1) were compared between singleton and twin TOLAC groups.

RESULTS

Ninety-five women with a twin gestation and one previous Cesarean delivery comprised the study group. Five thousand seven hundred and three women with a singleton gestation and one previous Cesarean delivery comprised the control group. 30.5% and 83% of women with twin and singleton gestation, respectively, underwent a trial of labor. Women in the twin TOLAC group were significantly less likely to succeed and less likely to have a spontaneous unassisted vaginal delivery compared to women in the singleton TOLAC group. Maternal age less than 35 years, parity greater than two, and at least one previous VBAC increased the likelihood of TOLAC success. Statistically significant differences were found between the twin TOLAC and the singleton TOLAC group for uterine rupture, maternal complications, and for combined adverse outcome.

CONCLUSIONS

Twin TOLAC is not common, even in parturients highly motivated for TOLAC. Our results demonstrate that even in a selected population, women undergoing twin TOLAC are less likely to have a successful spontaneous vaginal delivery and have a higher risk for uterine rupture, maternal complications, and combined adverse perinatal outcome than women undergoing TOLAC with a singleton gestation. Demographic and obstetric risk factors were identified which can aid the attending obstetrician in the counseling of these challenging cases.

摘要

目的

确定与剖宫产术后成功经阴道分娩(TOLAC)相关的因素。

方法

在一个对 TOLAC 意愿强烈的人群(>80%)的单一医疗中心进行了回顾性队列研究。分析了产妇人口统计学和产科特征对双胞胎 TOLAC 成功可能性的影响。比较了单胎 TOLAC 组和双胎 TOLAC 组的产妇并发症和复合不良结局(子宫破裂、5 分钟时 Apgar 评分<7 分和脐动脉 pH 值<7.1)。

结果

本研究纳入了 95 例双胎妊娠且有一次剖宫产史的孕妇作为研究组,5703 例单胎妊娠且有一次剖宫产史的孕妇作为对照组。分别有 30.5%和 83%的双胎和单胎妊娠孕妇尝试了 TOLAC。与单胎 TOLAC 组相比,双胎 TOLAC 组孕妇成功的可能性较小,且自然经阴道分娩的可能性较小。产妇年龄<35 岁、产次>2 次和至少有一次 VBAC 增加了 TOLAC 成功的可能性。双胎 TOLAC 组与单胎 TOLAC 组在子宫破裂、产妇并发症和复合不良围产结局方面存在统计学显著差异。

结论

即使在对 TOLAC 意愿强烈的产妇中,双胎 TOLAC 也并不常见。我们的结果表明,即使在选择人群中,与单胎妊娠 TOLAC 孕妇相比,行双胎 TOLAC 的孕妇自然经阴道分娩成功的可能性较低,子宫破裂、产妇并发症和复合不良围产结局的风险较高。确定了一些人口统计学和产科危险因素,有助于主治医生对这些有挑战性的病例进行咨询。

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