Ribeiro Igo B, Ngu Janet M C, Gill Gurinder, Rubens Fraser D
1 Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottowa, ON, Canada.
2 Division of Cardiovascular Perfusion, University of Ottawa Heart Institute, Ottowa, ON, Canada.
Perfusion. 2017 Oct;32(7):568-573. doi: 10.1177/0267659117709921. Epub 2017 May 21.
Development of a high-fidelity cardiac surgery simulator (CSS) requires integration of a heart model with a mock cardiopulmonary bypass (CPB) circuit that can provide feedback to mimic the pathophysiology of cardiac surgery. However, the cost of commercially available simulators precludes regular use. We describe steps in the construction of a high-fidelity CSS that integrates a pulsatile paracorporeal ventricular-assist device (Pulse-VAD) and a commercially available CPB simulator.
METHODS/RESULTS: Eight porcine hearts were initially prepared. The configuration consisted of cannulation of the distal descending aorta and the inferior vena cava to enable pressurization of the heart after connection to the Califia simulator, as well as Pulse-VAD cannulation (fitted with inflatable balloons) of both ventricles. After each simulation run, the team addressed key issues to derive successive model changes through consensus. Key modifications included: a) pressure maintenance of the cardiac chambers (removal of lungs, Pulse-VAD cannulation sites at the left pulmonary artery and vein, double ligation of arch vessels); b) high-fidelity beating of both ventricles (full Pulse-VAD bladder filling and ensuring balloon neck placement at the valvular plane) and c) reproducible management of porcine anatomy (management of porcine aorta, ligation of left azygous vein and shortened ascending thoracic aortic segment).
A CSS can be prepared at low cost, with integration into a high-fidelity CPB simulator with a novel beating heart component. This setup can be used in teaching the basics of CPB techniques and complex surgical procedures. Future work is needed to validate this model as a simulation instrument.
开发高保真心脏手术模拟器(CSS)需要将心脏模型与模拟体外循环(CPB)回路集成,该回路可提供反馈以模拟心脏手术的病理生理学。然而,市售模拟器的成本使其无法常规使用。我们描述了构建高保真CSS的步骤,该模拟器集成了脉动体外心室辅助装置(Pulse-VAD)和市售CPB模拟器。
方法/结果:最初准备了8个猪心脏。其配置包括在降主动脉远端和下腔静脉插管,以便在连接到Califia模拟器后对心脏进行加压,以及在两个心室进行Pulse-VAD插管(配备可充气气球)。每次模拟运行后,团队都会讨论关键问题,以通过共识得出后续的模型更改。关键修改包括:a)心脏腔室的压力维持(去除肺,在左肺动脉和静脉处进行Pulse-VAD插管部位,对弓状血管进行双重结扎);b)两个心室的高保真跳动(Pulse-VAD气囊完全充盈并确保气囊颈部放置在瓣膜平面)以及c)猪解剖结构的可重复管理(猪主动脉的管理,左奇静脉结扎和缩短胸段升主动脉)。
可以低成本制备CSS,并将其集成到具有新型跳动心脏组件的高保真CPB模拟器中。此设置可用于教授CPB技术基础和复杂手术程序。需要进一步开展工作以验证该模型作为模拟工具的有效性。