Perni Subha, Wang Tony J, Lesser Jerry, Mandigo Christopher, Isaacson Steven R, Horowitz David P
Department of Radiation Oncology, Columbia University/New York Presbyterian Hospital, New York, NY, USA.
Herbert Irving Comprehensive Cancer Center, Columbia University/New York Presbyterian Hospital, New York, NY, USA.
CNS Oncol. 2017 Apr;6(2):111-118. doi: 10.2217/cns-2016-0026.
Brain metastases (BM) of pancreatic origin are extremely rare. We review the literature around BM of pancreatic origin and describe a 38-year-old woman who developed BM 10 months after pancreaticoduodenectomy for treatment of pancreatic adenocarcinoma. She underwent resection and fractionated stereotactic radiotherapy followed by re-resection and Gamma Knife radiosurgery (GKRS) when the lesion recurred. She then developed two new BM, and was treated with GKRS. The patient is alive without progression 38 months after her most recent GKRS.
胰腺来源的脑转移瘤极为罕见。我们回顾了有关胰腺来源脑转移瘤的文献，并描述了一名38岁女性，她在接受胰十二指肠切除术治疗胰腺腺癌10个月后发生了脑转移瘤。她接受了手术切除和分次立体定向放射治疗，病变复发时又进行了再次切除和伽玛刀放射外科治疗（GKRS）。随后她又出现了两处新的脑转移瘤，并接受了GKRS治疗。在她最近一次接受GKRS治疗38个月后，患者仍存活且病情无进展。
