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骨科手术中类风湿药物的围手术期管理

Perioperative Management of Rheumatoid Medications in Orthopedic Surgery.

作者信息

Sindhu Kunal, Cohen Brian, Gil Joseph A

出版信息

Orthopedics. 2017 Sep 1;40(5):282-286. doi: 10.3928/01477447-20170518-04. Epub 2017 May 22.

Abstract

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder known to cause progressive joint destruction. Over time, untreated RA can lead to pain and increasing disability, making orthopedic intervention necessary. The treatment of RA revolves around a variety of medications that blunt the overall immune response. However, this may increase the risk of infection and impair wound healing. Given the nature of this disease, orthopedists frequently encounter patients with RA in the operative setting. To optimize surgical outcomes, orthopedists must carefully manage and pay special attention to the adverse side effects of the complicated medication regimens of these patients perioperatively. [Orthopedics. 2017; 40(5):282-286.].

摘要

类风湿性关节炎(RA)是一种慢性全身性自身免疫性疾病,已知会导致进行性关节破坏。随着时间的推移,未经治疗的类风湿性关节炎会导致疼痛和残疾加剧,因此需要进行骨科干预。类风湿性关节炎的治疗围绕着多种抑制整体免疫反应的药物展开。然而,这可能会增加感染风险并损害伤口愈合。鉴于这种疾病的性质,骨科医生在手术环境中经常会遇到类风湿性关节炎患者。为了优化手术效果,骨科医生必须在围手术期仔细管理并特别关注这些患者复杂药物治疗方案的不良副作用。[《骨科》。2017年;40(5):282 - 286。]

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