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评估营养状况作为胃肠手术后术后并发症和发病率的独立预测指标。

Evaluation of nutritional status as an independent predictor of post-operative complications and morbidity after gastro-intestinal surgery.

作者信息

van der Kroft G, Janssen-Heijnen M L G, van Berlo C L H, Konsten J L M

机构信息

Department of General, Gastrointestinal and Transplant Surgery, Uniklinik Aachen, Aachen, Germany.

Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands; Department of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.

出版信息

Clin Nutr ESPEN. 2015 Aug;10(4):e129-e133. doi: 10.1016/j.clnesp.2015.05.005. Epub 2015 Jun 19.

Abstract

BACKGROUND

Nutritional Risk Screening-2002 (NRS-2002) and the Malnutrition Universal Screening Tool (MUST) are screening tools for nutritional risk that have also been used to predict post-operative complications and morbidity, though not all studies confirm the reliability of nutritional screening. Our study aims to evaluate the independent predictive value of nutritional risk screening in addition to currently documented medical, surgical and anesthesiological risk factors for post-operative complications, as well as length of hospital stay.

METHODS

This study is a prospective observational cohort study of 129 patients undergoing elective gastro-intestinal-surgery. Patients were screened for nutritional risk upon admission using both MUST and NRS-2002 screening tools. Univariate and multivariate analyses were performed to investigate the independent predictive value of nutritional risk for post-operative complications and length of hospital stay.

RESULTS

MUST ≥2 (OR 2.87; 95% CI 1.05-7.87) and peri-operative transfusion (OR 2.78; 95% CI 1.05-7.40) were significant independent predictors for the occurrence of post-operative complications. Peri-operative transfusion (HR 2.40; 95% CI 1.45-4.00), age ≥70 (HR 1.50; 95% CI 1.05-2.16) and open surgery versus laparoscopic surgery (HR 1.39; 95% CI 0.94-2.05) were independent predictors for increased length of hospital stay, whereas American Society of Anesthesiology Score (ASA) and MUST were not.

CONCLUSION

Nutritional risk screening (MUST ≥2) is an independent predictor for post-operative complications, but not for increased length of hospital stay.

摘要

背景

2002年营养风险筛查(NRS - 2002)和营养不良通用筛查工具(MUST)是用于营养风险的筛查工具,也被用于预测术后并发症和发病率,不过并非所有研究都证实营养筛查的可靠性。我们的研究旨在评估营养风险筛查除目前已记录的医疗、外科和麻醉风险因素之外对术后并发症以及住院时间的独立预测价值。

方法

本研究是一项对129例行择期胃肠手术患者的前瞻性观察队列研究。患者入院时使用MUST和NRS - 2002筛查工具进行营养风险筛查。进行单因素和多因素分析以研究营养风险对术后并发症和住院时间的独立预测价值。

结果

MUST≥2(比值比2.87;95%置信区间1.05 - 7.87)和围手术期输血(比值比2.78;95%置信区间1.05 - 7.40)是术后并发症发生的显著独立预测因素。围手术期输血(风险比2.40;95%置信区间1.45 - 4.00)、年龄≥70岁(风险比1.50;95%置信区间1.05 - 2.16)以及开腹手术与腹腔镜手术相比(风险比1.39;95%置信区间0.94 - 2.05)是住院时间延长的独立预测因素,而美国麻醉医师协会评分(ASA)和MUST则不是。

结论

营养风险筛查(MUST≥2)是术后并发症的独立预测因素,但不是住院时间延长的独立预测因素。

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