Eades Claire E, Cameron Dawn M, Evans Josie M M
Faculty of Health Sciences and Sport, University of Stirling, United Kingdom.
Faculty of Health Sciences and Sport, University of Stirling, United Kingdom.
Diabetes Res Clin Pract. 2017 Jul;129:173-181. doi: 10.1016/j.diabres.2017.03.030. Epub 2017 May 9.
Estimates of the prevalence of gestational diabetes vary widely. It is important to have a clear understanding of the prevalence of this condition to be able to plan interventions and health care provision. This paper describes a meta-analysis of primary research data reporting the prevalence of gestational diabetes mellitus in the general pregnant population of developed countries in Europe.
Four electronic databases were systematically searched in May 2016. English language articles reporting gestational diabetes mellitus prevalence using universal screening in general pregnant population samples from developed countries in Europe were included. All papers identified by the search were screened by one author, and then half screened independently by a second author and half by a third author. Data were extracted by one author. Values for the measures of interest were combined using a random effects model and analysis of the effects of moderator variables was carried out.
A total of 3258 abstracts were screened, with 40 studies included in the review. Overall prevalence of gestational diabetes mellitus was 5.4% (3.8-7.8). Maternal age, year of data collection, country, area of Europe, week of gestation at testing, and diagnostic criteria were found to have a significant univariate effect on GDM prevalence, and area, week of gestation at testing and year of data collection remained statistically significant in multivariate analysis. Quality category was significant in multivariate but not univariate analysis.
This meta-analysis shows prevalence of GDM that is at the upper end of previous estimates in Europe.
妊娠期糖尿病患病率的估计值差异很大。清楚了解这种疾病的患病率对于规划干预措施和医疗保健服务至关重要。本文描述了一项对主要研究数据的荟萃分析，这些数据报告了欧洲发达国家普通孕妇群体中妊娠期糖尿病的患病率。
2016年5月对四个电子数据库进行了系统检索。纳入了在欧洲发达国家普通孕妇样本中使用通用筛查报告妊娠期糖尿病患病率的英文文章。由一位作者对检索到的所有论文进行筛选，然后由第二位作者独立筛选一半，第三位作者筛选另一半。由一位作者提取数据。使用随机效应模型对感兴趣的测量值进行合并，并对调节变量的效应进行分析。
共筛选了3258篇摘要，该综述纳入了40项研究。妊娠期糖尿病的总体患病率为5.4%（3.8 - 7.8）。发现产妇年龄、数据收集年份、国家、欧洲地区、检测时的孕周以及诊断标准对妊娠期糖尿病患病率有显著的单变量效应，在多变量分析中，地区、检测时的孕周和数据收集年份仍具有统计学意义。质量类别在多变量分析中具有显著性，但在单变量分析中不具有显著性。
这项荟萃分析显示，妊娠期糖尿病的患病率处于欧洲先前估计值的上限。
