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摩洛哥妊娠期糖尿病孕妇的随访及危险因素

Follow-up and risk factors of pregnant women with gestational diabetes in Morocco.

作者信息

Boutiti Rachida, Gougueni Hicham, Bouchriti Youssef, Arechkik Abderrahman, Mahlaq Safiya, Iziki Hayat, Barkat Amina

机构信息

Health and Nutrition of the Mother and Child Couple Research Team, Faculty of Medicine and Pharmacy, Mohamed V. University, Rabat, Morocco.

Department of Midwifery, High Institute of Nursing Professions and Health Techniques, Agadir, Morocco.

出版信息

J Public Health Afr. 2025 Aug 25;16(1):1313. doi: 10.4102/jphia.v16i1.1313. eCollection 2025.

Abstract

BACKGROUND

Gestational diabetes mellitus (GDM) represents a significant global public health challenge, posing substantial risks to both maternal and foetal health.

AIM

This study analysed risk factors, follow-up, management approaches and obstetric complications in pregnant women with GDM.

SETTING

This study was conducted in Southern Morocco.

METHODS

This multicentre retrospective cross-sectional study analysed 297 patient files ( = 120 with GDM) from four maternity hospitals (2019-2023). Data were collected via a standardised form. Statistical analysis included descriptive summaries, group comparisons (Chi-square, Fisher's -test, Mann-Whitney ) and logistic regression to calculate odds ratios (ORs) using SPSS version 27.

RESULTS

Gestational diabetes mellitus screening was inconsistent: only 17% (95% confidence interval [CI]: 11.5% - 25.6%) of women were screened before 24 weeks of amenorrhea, and 38% (95% CI: 29.8% - 47.5%) between 24 weeks and 28 weeks. The oral glucose tolerance test 75 g was not used. Gestational diabetes mellitus was significantly associated with caesarean delivery (OR = 2.52; 95% CI: 1.29-4.92; = 0.007 and preeclampsia 5.95 (95% CI: 1.21-29.21; = 0.028). Risk factors for GDM included maternal age over 35 years and obesity (body mass index [BMI]: ≥ 30). A history of prematurity showed a significant association with GDM, with adjuster OR (aOR) of 3.47 (95% CI: 1.36-8.79; < 0.011).

CONCLUSION

Preventing maternal complications from GDM relies on raising women's awareness about the importance of screening and monitoring during pregnancy in Southern Morocco.

CONTRIBUTION

This study highlights the necessity of strengthening GDM screening and targeted management strategies for at-risk pregnant women in Morocco, particularly in the southern region.

摘要

背景

妊娠期糖尿病(GDM)是一项重大的全球公共卫生挑战,对孕产妇和胎儿健康均构成重大风险。

目的

本研究分析了妊娠期糖尿病孕妇的风险因素、随访情况、管理方法及产科并发症。

地点

本研究在摩洛哥南部开展。

方法

这项多中心回顾性横断面研究分析了四家妇产医院(2019 - 2023年)的297份患者档案(n = 120例妊娠期糖尿病患者)。数据通过标准化表格收集。统计分析包括描述性总结、组间比较(卡方检验、费舍尔精确检验、曼 - 惠特尼U检验)以及使用SPSS 27版本进行逻辑回归以计算比值比(OR)。

结果

妊娠期糖尿病筛查情况不一致:仅17%(95%置信区间[CI]:11.5% - 25.6%)的女性在停经24周前接受了筛查,38%(95% CI:29.8% - 47.5%)在24周和28周之间接受了筛查。未使用75克口服葡萄糖耐量试验。妊娠期糖尿病与剖宫产显著相关(OR = 2.52;95% CI:1.29 - 4.92;P = 0.007)以及子痫前期(OR = 5.95;95% CI:1.21 - 29.21;P = 0.028)。妊娠期糖尿病的风险因素包括产妇年龄超过35岁和肥胖(体重指数[BMI]:≥ 30)。早产史与妊娠期糖尿病显著相关,校正后OR(aOR)为3.47(95% CI:1.36 - 8.79;P < 0.011)。

结论

预防妊娠期糖尿病所致的孕产妇并发症依赖于提高摩洛哥南部女性对孕期筛查和监测重要性的认识。

贡献

本研究强调了在摩洛哥,尤其是南部地区,加强妊娠期糖尿病筛查及针对高危孕妇的靶向管理策略实施的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c015/12421584/8945fdb6db77/JPHIA-16-1313-g001.jpg

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