Fabrication of vinyl organosilicon @poly-N, N'-[(4, 5-dihydroxy-1, 2-phenylene)bis(methylene)]bisacrylamide) core@shell antibacterial agent.
作者信息
Zhang Zhijia, Zhao Xiaole, Su Yingchun, Xing Defeng, Han Xiaojun
机构信息
MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin 150001, China.
State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, 92 West Da-Zhi Street, Harbin 150001, China.
出版信息
Mater Sci Eng C Mater Biol Appl. 2017 Aug 1;77:624-629. doi: 10.1016/j.msec.2017.04.001. Epub 2017 Apr 1.
We demonstrate that antibacterial agent N, N'-[(4, 5-dihydroxy-1, 2-phenylene)bis(methylene)]bisacrylamide (OHABA) can be assembled on the surface of vinyl organosilicon nanospheres (VOSNs) by atom transfer radical polymerization (ATRP). Chemically cross-linked vinyl organosilicon cores were facilely fabricated by sol-gel method as support, which densely grafted poly-OHABA (POHABA) as shells. Antibacterial assessment test results revealed that POHABA-based core@shell structure displayed high antibacterial performance, long-term stability, and kept broad-spectrum antibacterial effect of against Gram-negative and Gram-positive bacteria.
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