Controllable synthesis FeO@POHABA core-shell nanostructure as high-performance recyclable bifunctional magnetic antimicrobial agent.

We demonstrated a method to form magnetic antimicrobial POHABA (poly-N,N'-[(4,5-dihydroxy-1,2-phenylene)bis(methylene)]bisacrylamide)-based core-shell nanostructure by free-radical polymerization of OHABA on the FeO core surface. The magnetic antimicrobial agent FeO@POHABA can be used in domestic water treatment against bacterial pathogens. The thickness of POHABA shell could be controlled from 10.4 ± 1.2 to 56.3 ± 11.7 nm by the dosage of OHABA. The results of antimicrobial-activity test indicated that POHABA-based core-shell nanostructure had broad-spectrum inhibitory against Gram-negative, Gram-positive bacteria and fungi. The minimum inhibitory concentration (MIC) values of FeO@POHABA nanostructure against Escherichia coli and Bacillus subtilis were both 0.4 mg/mL. FeO@POHABA nanostructures responded to a permanent magnet and were easily recycled. FeO@POHABA nanoparticles retained 100% antimicrobial efficiency for both Gram-negative and Gram-positive bacteria throughout eight recycle procedures.