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Primer in Genetics and Genomics, Article 4-Inheritance Patterns.

作者信息

Aiello Lisa B, Chiatti Beth Desaretz

机构信息

1 College of Nursing and Health Professions, Drexel University, Philadelphia, PA, USA.

出版信息

Biol Res Nurs. 2017 Jul;19(4):465-472. doi: 10.1177/1099800417708616. Epub 2017 May 22.

Abstract

Since the completion of the Human Genome Project, much has been uncovered about inheritance of various illnesses and disorders. There are two main types of inheritance: Mendelian and non-Mendelian. Mendelian inheritance includes autosomal dominant, autosomal recessive, X-linked, and Y-linked inheritance. Non-Mendelian inheritance includes mitochondrial and multifactorial inheritance. Nurses must understand the types of inheritance in order to identify red flags that may indicate the possibility of a hereditary disorder in a patient or family.

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