Robillard Pierre-Yves, Hulsey Thomas C, Boukerrou Malik, Bonsante Francesco, Dekker Gustaaf, Iacobelli Silvia
a Service de Néonatologie , Centre Hospitalier Universitaire Sud Réunion , Saint-Pierre , France.
b Centre d'Etudes Périnatales Océan Indien (CEPOI) , Centre Hospitalier Universitaire Sud Réunion , Saint-Pierre , France.
J Matern Fetal Neonatal Med. 2018 Aug;31(15):2027-2035. doi: 10.1080/14767058.2017.1334049. Epub 2017 Jun 26.
We sought to investigate the potential association between maternal age and the need for active obstetrical intervention intrapartum in primiparas.
Observational study over 14 years (2001-2014) of all consecutive primiparous singleton births having delivered at the Centre Hospitalier Universitaire Hospitalier Sud Reunion's maternity (French overseas department, Indian Ocean).
Of the 21,235 singleton primiparous births, there were three significant linear associations between maternal age from 12 years of age to 42 + (all χ for linear trend, p < .0001) (a) vaginal deliveries without any medical intervention, (b) rate of cesarean sections, and (c) rate of operative vaginal procedures. These three linear associations persisted when controlling for maternal obesity (±30 kg/m), "heavy babies" (>3.5 kg), and ethnicity. Using maternal age remained significantly an independent risk factor (p < .0001), after controlling for the major confounders: maternal BMI, maternal height, birthweight ≥3500 g, p < .0001.
Increasing maternal age has a linear association with vaginal deliveries without any medical intervention, rate of cesarean sections, and rate of operative vaginal procedures. These associations are independent of maternal BMI and maternal height. We currently do not have a specific explanation why younger women appear to be protected from requiring intrapartum obstetric intervention. Nevertheless, these strong facts deserve acknowledgement and further research.
我们试图研究初产妇的母亲年龄与产时积极产科干预需求之间的潜在关联。
对在留尼汪大学医院南区医院产科(法国海外省,印度洋地区)分娩的所有连续初产单胎分娩进行了为期14年(2001 - 2014年)的观察性研究。
在21,235例初产单胎分娩中,母亲年龄从12岁至42岁以上之间存在三种显著的线性关联(所有线性趋势的χ检验,p < 0.0001):(a)无任何医学干预的阴道分娩,(b)剖宫产率,以及(c)阴道助产手术率。在控制母亲肥胖(±30 kg/m²)、“巨大儿”(>3.5 kg)和种族因素后,这三种线性关联仍然存在。在控制了主要混杂因素(母亲BMI、母亲身高、出生体重≥3500 g,p < 0.0001)后,母亲年龄仍然是一个显著的独立危险因素(p < 0.0001)。
母亲年龄增加与无任何医学干预的阴道分娩、剖宫产率和阴道助产手术率呈线性关联。这些关联独立于母亲BMI和母亲身高。目前我们没有具体解释为什么年轻女性似乎较少需要产时产科干预。然而,这些确凿的事实值得认可和进一步研究。