[Non-polio enterovirus in France from 1974 to 1985. Data collected from a system of 30 hospital virology laboratories].

A total of 12,097 isolates of NPEV was reported in France from 1974 through 1985 by 30 volunteers laboratories (71% of all virology laboratories). The 14 most common types which accounted for 75% of all isolates are echoviruses 4, 6, 7, 9, 11, 14, 30 and 33, coxsackieviruses A9, B1 to B5. Among them, 12 are equally reported as the most common types isolated in the United States from 1970 through 1983. Echoviruses 14 and 33 are specially found in France; Echoviruses 3 and 5 in the United States. We can estimate that those 16 types are the most common EVNP in human pathology. The pattern of each type is different in the United States and in France: it seems not possible to assign an epidemic character specific to each of them. Yet epidemic types accounted for 13 to 27% of isolates in March, April, May. Among clinical manifestations, aseptic meningitis are the most frequently reported: 37% of 3,619 cases. Echoviruses are significantly most often associated with meningitis than coxsackieviruses (p less than 0.001) and coxsackieviruses more often associated with other neurological manifestations, myocarditis and pericarditis. From these results wa can suggest to simplify the typing procedures of NPEV for routine diagnosis.