Kamaleshwaran Koramadai Karuppusamy, Joseph Jephy, Kalarikal Radhakrishnan, Shinto Ajit Sugunan
Department of Nuclear Medicine and PET/CT, Comprehensive Cancer Care Center, Kovai Medical Center and Hospital Limited, Coimbatore, India.
Indian J Nucl Med. 2017 Apr-Jun;32(2):137-139. doi: 10.4103/0972-3919.202237.
Fibrous dysplasia (FD) of the bone is characterized by the medullary cavity of bones becoming filled with fibrous tissue, and its etiology remains unknown. It is usually asymptomatic and found incidentally on imaging studies that are performed for other purposes. FD may closely mimic the appearance of bony metastatic disease on radiological examinations. We report the case of a 45-year-old female patient, which appeared to have multiple bone lesions on initial workup images. Subsequently, the bone lesions that showed increased FDG uptake on PET/CT in right femur and tibia were identified as FD. The present case is a useful addition to the current body of literature of false positive F-18 FDG PET/CT due to a benign skeletal pathology and underscores the importance of high index of suspicion and careful correlation, whenever one comes across such an unusual PET/CT finding.
骨纤维异常增殖症（FD）的特征是骨髓腔被纤维组织填充，其病因尚不清楚。它通常无症状，在因其他目的进行的影像学检查中偶然发现。在放射学检查中，FD可能与骨转移瘤的表现极为相似。我们报告一例45岁女性患者，其初始检查影像显示有多处骨病变。随后，在PET/CT上右股骨和胫骨FDG摄取增加的骨病变被确诊为FD。该病例为目前因良性骨骼病变导致F-18 FDG PET/CT假阳性的文献增添了内容，并强调了每当遇到此类不寻常的PET/CT表现时，保持高度怀疑和仔细对比的重要性。
