Trimarchi Santi, Kamman Arnoud, Lomazzi Chiara, Segreti Sara, Cova Marta, De Vincentiis Carlo, Frigiola Alessandro, Menicanti Lorenzo, Marrocco-Trischitta Massimiliano M, Grassi Viviana, Morganti Simone, Conti Michele, Auricchio Ferdinando, Rampoldi Vincenzo
Section of Vascular Surgery II°, Thoracic Aortic Research Center, Policlinico San Donato IRCCS, University of Milan, Piazza Malan 2, 20097 San Donato Milanese, Milan, Italy.
Section of Cardiac Surgery, Thoracic Aortic Research Center, Policlinico San Donato IRCCS, San Donato Milanese, Milan, Italy.
Eur Heart J Suppl. 2016 Apr 28;18(Suppl E):E57-E63. doi: 10.1093/eurheartj/suw015. Epub 2016 Apr 29.
The Thoracic Aortic Research Center (TARC) of the IRCCS Policlinico San Donato (PSD) aims to promote research on thoracic aortic diseases, to disclose the scientific knowledge and clinical experience and to develop new scientific paths within the Hospital and the aortic community, in collaboration with other national and international centres. Thoracic Aortic Research Center collaborates with many centres in both Europe (e.g. University of Utrecht, the Netherlands) and the USA (e.g. University of Michigan). This has led to multiple highly regarded publications in respected cardiovascular journals and has led to several PhD programmes resulting in doctorate degrees. Within Italy, in association with the Bioengineering School of the University of Pavia, TARC has founded the "BETA-lab" (iomechanics for ndovascular reatment of the orta laboratory), where MDs, Bioengineers, and PhD fellows conduct experimental studies using models of the physiologic aorta and aortic diseases. Furthermore, a database (iCardiocloud) where the medical imaging of cardiovascular patients from the PSD is structured, for analysis utilizing computational fluid dynamics, and studies using also 3D printed aortic models. With the role of principal investigator or co-investigator, TARC at PSD has been participating in other several projects, including the International Registry of Acute Aortic Dissection, the International Aortic Arch Surgery Study Group, the European Registry of Endovascular Aortic Repair Complications, the ADSORB and ASSIST trials, and the GREAT registry. International collaborations have included also studies on predictors of aortic growth after dissection with the Yale University and University of Virginia, and on aortic biomarkers with the University of Tokyo.
圣多纳托综合医院（IRCCS Policlinico San Donato，PSD）的胸主动脉研究中心（TARC）旨在推动胸主动脉疾病的研究，传播科学知识和临床经验，并在医院及主动脉领域开拓新的科学路径，与其他国内和国际中心展开合作。胸主动脉研究中心与欧洲（如荷兰乌得勒支大学）和美国（如密歇根大学）的许多中心开展合作。这促成了在备受尊敬的心血管期刊上发表多篇高影响力的论文，并催生了多个授予博士学位的博士项目。在意大利，TARC与帕维亚大学的生物工程学院合作，成立了“BETA实验室”（用于主动脉血管内治疗的生物力学实验室），医学博士、生物工程师和博士生在此使用生理主动脉和主动脉疾病模型进行实验研究。此外，还建立了一个数据库（iCardiocloud），对PSD心血管患者的医学影像进行结构化处理，以便利用计算流体动力学进行分析，并使用3D打印的主动脉模型进行研究。作为主要研究者或共同研究者，PSD的TARC参与了其他多个项目，包括国际急性主动脉夹层注册研究、国际主动脉弓手术研究组、欧洲血管内主动脉修复并发症注册研究、ADSORB和ASSIST试验以及GREAT注册研究。国际合作还包括与耶鲁大学和弗吉尼亚大学合作开展的关于主动脉夹层后主动脉生长预测因素的研究，以及与东京大学合作开展的关于主动脉生物标志物的研究。
