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约旦尸检病例中血源病毒感染的患病率。

Prevalence of blood-borne viral infections among autopsy cases in Jordan.

作者信息

Bakri Faris G, Al-Abdallat Imad M, Ababneh Nidaa, Al Ali Rayyan, Idhair Ahmed K F, Mahafzah Azmi

机构信息

Infectious Diseases and Vaccine Center, Department of Medicine - Division of Infectious Diseases, Jordan University Hospital, University of Jordan, Amman, Jordan.

Department of Forensic Medicine, Jordan University Hospital, University of Jordan, Amman, Jordan.

出版信息

Qatar Med J. 2017 Apr 21;2016(2):14. doi: 10.5339/qmj.2016.14. eCollection 2016.

DOI:10.5339/qmj.2016.14
PMID:28534006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5427512/
Abstract

Morgues are high risk areas for the spread of infection from cadavers to staff during the post-mortem examination. Infection can spread from corpses to workers by airborne transmission, by direct contact, or through needle and sharp object injuries. Knowledge about the prevalence of these infections on autopsy is essential to determine the risk of transmission and to further enforce safety measures. This is a descriptive study. All autopsies performed in the Department of Forensic Medicine at Jordan University Hospital during the study period were tested for the serology of human immunodeficiency, hepatitis B and C viruses. Positive tests were confirmed by nucleic acid testing. A total of 242 autopsies were tested. Age ranged from 3 days to 94 years (median 75.5 years, mean 45.3 years (21.9 ±  SD)). There were 172 (71%) males. The cause of death was considered natural in 137 (56.6%) cases, accidental in 89 (36.8%), homicide in nine (3.7%), suicide in four (1.7%), and unknown in three (1.2%) cases. Hepatitis B surface antigen was positive in five (2.1%) cases. Hepatitis C virus antibody was positive in five (2.1%) cases and the hepatitis C virus polymerase chain reaction was positive in two (0.8%) cases. HIV antibody was not detected in any of the cases. The infection status of cases was not associated with age, sex, nationality, or cause of death. The study findings indicated that there is a low prevalence of virus-infected autopsies in Jordan. However, the risk of transmission remains a potential threat and therefore the necessary precautions should always be taken during autopsy.

摘要

在尸体解剖检查期间,太平间是感染从尸体传播给工作人员的高风险区域。感染可通过空气传播、直接接触或针头及锐器损伤从尸体传播给工作人员。了解这些感染在尸检中的流行情况对于确定传播风险和进一步加强安全措施至关重要。这是一项描述性研究。对研究期间在约旦大学医院法医学系进行的所有尸检进行了人类免疫缺陷病毒、乙型肝炎病毒和丙型肝炎病毒的血清学检测。阳性检测结果通过核酸检测进行确认。共检测了242例尸检。年龄范围为3天至94岁(中位数75.5岁,平均45.3岁(21.9 ±标准差))。有172例(71%)为男性。137例(56.6%)的死亡原因被认为是自然死亡,89例(36.8%)为意外死亡,9例(3.7%)为他杀,4例(1.7%)为自杀,3例(1.2%)死因不明。5例(2.1%)乙型肝炎表面抗原呈阳性。5例(2.1%)丙型肝炎病毒抗体呈阳性,2例(0.8%)丙型肝炎病毒聚合酶链反应呈阳性。所有病例均未检测到HIV抗体。病例的感染状况与年龄、性别、国籍或死亡原因无关。研究结果表明,约旦病毒感染尸检的患病率较低。然而,传播风险仍然是一个潜在威胁,因此在尸检期间应始终采取必要的预防措施。

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