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乳腺癌转移管理的最新观点——最新进展

Recent perspectives of management of breast cancer metastasis - an update.

作者信息

Tian Qingzhong, Wang Yun, Guo Hao, Xie Guangwei, Li Jin, Zhang Minkang, Zhang Qianjin, Meng Qingliang

机构信息

Department of Oncological Surgery 2, Xuzhou City Central Hospital, the affiliated Hospital of the Southeast University Medical School (Xu zhou), the Tumor Research Institute of the Southeast University (Xu zhou), Xuzhou Jiangsu 221009, China.

出版信息

J BUON. 2017 Mar-Apr;22(2):295-300.

PMID:28534347
Abstract

Breast cancer is the leading cause of cancer related deaths in women and one of the most common cancers globally. The major obstacle in the management of breast cancer, especially at advanced stages, is metastasis. Metastasis in the advanced stages of breast cancer could decrease survival to approximately 5 years. The reasons could include lack of targeted receptors or chemotherapeutic agents for the management of advanced-stage breast cancer metastasis. The new emerging avenues for the management of this deadly pathological state include local manipulations like radiofrequency ablation (RFA), microwave thermotherapy, cryosurgery (cryotherapy), chemoembolization, radioembolization, breast surgery, or metastasectomy. Few single-institution reports showed improved survival in selected patients like those with oligometastatic stage IV breast cancer. The present review article focused on these emerging new multimodality treatment approaches for a possible efficient management.

摘要

乳腺癌是女性癌症相关死亡的主要原因,也是全球最常见的癌症之一。乳腺癌治疗,尤其是晚期治疗的主要障碍是转移。乳腺癌晚期的转移会使生存率降至约5年。原因可能包括缺乏用于治疗晚期乳腺癌转移的靶向受体或化疗药物。治疗这种致命病理状态的新出现途径包括局部操作,如射频消融(RFA)、微波热疗、冷冻手术(冷冻疗法)、化学栓塞、放射性栓塞、乳房手术或转移灶切除术。少数单机构报告显示,在某些患者中,如寡转移的IV期乳腺癌患者,生存率有所提高。本综述文章重点关注这些新出现的多模态治疗方法,以期实现可能的有效管理。

相似文献

1
Recent perspectives of management of breast cancer metastasis - an update.乳腺癌转移管理的最新观点——最新进展
J BUON. 2017 Mar-Apr;22(2):295-300.
2
Breast cancer metastasis.乳腺癌转移。
Cancer Genomics Proteomics. 2012 Sep-Oct;9(5):311-20.
3
The prevention and management of distant metastases in women with breast cancer.乳腺癌女性远处转移的预防与管理
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Novel treatment options in the management of metastatic breast cancer.转移性乳腺癌治疗的新选择
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Targeting metastatic and advanced breast cancer.靶向转移性和晚期乳腺癌。
Semin Oncol Nurs. 2007 Feb;23(1):37-45. doi: 10.1016/j.soncn.2006.11.007.
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Therapeutic approaches in young women with advanced or metastatic breast cancer.
Breast Cancer Res Treat. 2010 Sep;123 Suppl 1:49-52. doi: 10.1007/s10549-010-1071-0. Epub 2010 Aug 14.
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Has first-line therapy had an impact on general outcome in metastatic breast cancer?一线治疗对转移性乳腺癌的总体结局有影响吗?
Future Oncol. 2007 Aug;3(4):411-8. doi: 10.2217/14796694.3.4.411.
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The curability of breast cancer and the treatment of advanced disease.乳腺癌的可治愈性及晚期疾病的治疗
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[Therapy of metastasizing breast cancer].[转移性乳腺癌的治疗]
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New developments in metastatic breast cancer: general discussion.转移性乳腺癌的新进展:综述
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引用本文的文献

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MEAI: an artificial intelligence platform for predicting distant and lymph node metastases directly from primary breast cancer.MEAI:一个人工智能平台,可直接从原发性乳腺癌预测远处转移和淋巴结转移。
J Cancer Res Clin Oncol. 2023 Sep;149(11):9229-9241. doi: 10.1007/s00432-023-04787-y. Epub 2023 May 18.
2
Extracellular Matrix: Emerging Roles and Potential Therapeutic Targets for Breast Cancer.细胞外基质:乳腺癌的新作用及潜在治疗靶点
Front Oncol. 2021 Apr 22;11:650453. doi: 10.3389/fonc.2021.650453. eCollection 2021.
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A multicenter randomized controlled trial to assess the efficacy of cancer green therapy in treatment of stage IIIb/IV non-small cell lung cancer.
一项评估癌症绿色疗法治疗Ⅲb/Ⅳ期非小细胞肺癌疗效的多中心随机对照试验。
Medicine (Baltimore). 2020 Aug 14;99(33):e21626. doi: 10.1097/MD.0000000000021626.
4
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment.TMPRSS4的下调通过细胞周期和细胞凋亡过程的损害增强三阴性乳腺癌细胞的放射敏感性。
Asian Pac J Cancer Prev. 2019 Dec 1;20(12):3679-3687. doi: 10.31557/APJCP.2019.20.12.3679.
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Metastatic cancer cell attachment to endothelium is promoted by endothelial glycocalyx sialic acid degradation.内皮糖萼唾液酸降解促进转移性癌细胞与内皮细胞的黏附。
AIChE J. 2019 Aug;65(8). doi: 10.1002/aic.16634. Epub 2019 May 9.
6
Endothelial barrier reinforcement relies on flow-regulated glycocalyx, a potential therapeutic target.内皮屏障增强依赖于血流调节的糖萼,这是一个潜在的治疗靶点。
Biorheology. 2019;56(2-3):131-149. doi: 10.3233/BIR-180205.