Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cancer Genomics Proteomics. 2012 Sep-Oct;9(5):311-20.
Breast cancer metastasis accounts for the majority of deaths from breast cancer. Detection of breast cancer metastasis at the earliest stage is important for the management and prediction of breast cancer progression. Emerging techniques using the analysis of circulating tumor cells show promising results in predicting and identifying the early stages of breast cancer metastasis in patients. Additionally, a deeper understanding of the metastatic cascade in breast cancer will be critical for developing therapeutic interventions to combat breast cancer metastasis. In this review, the current and novel methods for detection of breast cancer metastasis, as well as the mechanisms involved in metastasis and the treatment of breast cancer metastasis, are discussed.
乳腺癌转移是导致乳腺癌死亡的主要原因。早期发现乳腺癌转移对于乳腺癌的治疗和预测进展至关重要。利用循环肿瘤细胞分析的新兴技术在预测和识别乳腺癌转移的早期阶段方面显示出了良好的效果。此外，深入了解乳腺癌转移级联反应对于开发治疗乳腺癌转移的干预措施至关重要。在这篇综述中，讨论了目前和新颖的乳腺癌转移检测方法，以及转移涉及的机制和乳腺癌转移的治疗方法。
