Zielinski C, Stingl G, Groh V, Guggenberger K, Kollegger H, Konrad K, Mayerhofer S, Presslich O, Schenk P, Steiner B
Universitäts-Hautklinik, Wien.
Wien Klin Wochenschr. 1988 Oct 21;100(20):668-72.
This study presents a report on the first clinical experiences gained in 68 hospitalized HIV antibody-positive patients from Austria, covering a period of twelve months. 36 patients (52.9%) belonged to risk group I or Ib (homo- or bisexual), whereas 26 (38.2%) patients were i.v. drug abusers (risk group II). 5 (7.4%) patients fulfilled the criteria of stage II of the CDC classification of HIV-associated clinical symptoms, 10 (14.7%) were classified as stage III and the remaining 53 patients (78%) as stage IV. The most frequent and also the most serious problem was the development of opportunistic infections. Multiple infections were found in 45.7% of all cases. Kaposi's sarcoma was found in 9 patients who all belonged to risk group I. During the entire observation period 10 patients died as a consequence of HIV-1-induced immunodeficiency and the resulting opportunistic infections and/or neoplasms.
本研究报告了对来自奥地利的68名住院HIV抗体阳性患者在12个月期间获得的首批临床经验。36名患者(52.9%)属于风险组I或Ib(同性恋或双性恋),而26名(38.2%)患者为静脉注射吸毒者(风险组II)。5名(7.4%)患者符合美国疾病控制与预防中心(CDC)HIV相关临床症状分类第二阶段的标准,10名(14.7%)被分类为第三阶段,其余53名患者(78%)为第四阶段。最常见也是最严重的问题是机会性感染的发生。在所有病例中,45.7%发现有多种感染。9名患者发现患有卡波西肉瘤,他们均属于风险组I。在整个观察期内,10名患者因HIV-1引起的免疫缺陷以及由此导致的机会性感染和/或肿瘤而死亡。