Department of Biology, Colorado State University, Fort Collins, CO 80523, USA; Cell and Molecular Biology Program, Colorado State University, Fort Collins, CO 80523, USA.
Department of Biology, Colorado State University, Fort Collins, CO 80523, USA.
Curr Biol. 2017 May 22;27(10):R383-R385. doi: 10.1016/j.cub.2017.03.061.
Reversible changes in gene expression independent of the genetic code can be transmitted from one generation to the next via poorly understood mechanisms. In worms, a histone-modifying enzyme is necessary to keep small RNA-guided transgenerational gene silencing in check.
基因表达的可逆变化独立于遗传密码,可以通过尚未完全了解的机制从一代传递到下一代。在蠕虫中,一种组蛋白修饰酶对于控制小 RNA 指导的跨代基因沉默是必需的。