从Sieb.中分离得到的二聚倍半萜类化合物——静香醇C和F的抗真菌活性
Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Sieb.
作者信息
Kang Tae Hoon, Lee Yun Mi, Lee Won Jung, Hwang Eui Il, Park Ki Duk, Choi Gyang Ja, Moon Jae Sun, Park Ho-Yong, Kim Sung Uk
机构信息
Industrial Bio-materials Research Center, KRIBB, Daejeon 34141, Republic of Korea.
Technical Research Center, KT&G R&D Headquaters, Daejeon 34128, Republic of Korea.
出版信息
J Microbiol Biotechnol. 2017 Jul 28;27(7):1272-1275. doi: 10.4014/jmb.1612.12051.
Two dimeric sesquiterpenes were separated from Sieb. and identified as shizukaols C and F. They exhibited potent antifungal activities (MICs = 4-16 μg/ml) in vitro against various plant pathogenic fungi ( and ). Shizukaol C showed 88% and 91% protective activities in the greenhouse against (wheat leaf rust) and (tomato late blight), respectively, at 100 μg/ml; shizukaol F exhibited 93% antifungal activity against at the same concentration. Therefore, these compounds might serve as interesting candidates for effective antifungal agents.
从Sieb.中分离出两种二聚倍半萜，并鉴定为静香醇C和F。它们在体外对多种植物病原真菌表现出强大的抗真菌活性（最低抑菌浓度=4-16μg/ml）。静香醇C在温室中对小麦叶锈菌和番茄晚疫病分别在100μg/ml时表现出88%和91%的保护活性；静香醇F在相同浓度下对番茄晚疫病表现出93%的抗真菌活性。因此，这些化合物可能是有效的抗真菌剂的有趣候选物。
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