Gawaziuk Justin Peter, Liu Tianyi, Sigurdson Leif, Buchel Edward, Hayakawa Thomas Edward Jo, Shiga Sarah, Logsetty Sarvesh
Manitoba Firefighters' Burn Unit, Health Sciences Centre, Winnipeg, Manitoba, Canada.
Section of Plastic Surgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Burns. 2017 Nov;43(7):1561-1566. doi: 10.1016/j.burns.2017.04.007. Epub 2017 May 20.
Necrotizing fasciitis (NF) is a life-threatening infection requiring extensive debridement that may necessitate amputation. Free tissue transfer (FTT) is an option for reconstruction in difficult cases. Currently, only case reports have described FTT in the setting of NF, and comprehensive evidence on flap outcomes is lacking. The present study characterizes outcomes in patients with FTT following NF.
All patients admitted with NF between January 1, 2005 and December 31, 2011 to our level 1 burns/trauma referral center were retrospectively reviewed.
No significant difference was found in patient demographics between FTT (n=12) and no FTT (n=212). Both groups had the same number of operations, same length of ICU stay, and length of hospitalization. The flaps used were 10 anterolateral thigh, 1 latissimus dorsi and 1 radial forearm. Recipient sites included: upper extremities (6), lower extremities (4), head/neck (1), and genitalia (1). No flap failures and no take-back operations were required. Upper extremities comprised 58.3% of FTT patients compared to 18.9% (p=0.004) in non-FTT patients. Flap operations occurred a mean of 11.6days post-admission with 1.1 operations prior to FTT. Mean FTT size was 213cm. Flap complications included seroma (n=1), hematoma (n=1). Donor site complications included hematoma (n=1), exposed tendon (n=1) and necrosis (n=1).
This study demonstrates that FTT provides a promising reconstructive option in the setting of NF without adversely affecting patient outcome.
坏死性筋膜炎(NF)是一种危及生命的感染,需要广泛清创,甚至可能需要截肢。对于复杂病例,游离组织移植(FTT)是一种重建选择。目前,仅有病例报告描述了NF患者的FTT情况,缺乏关于皮瓣预后的全面证据。本研究描述了NF患者接受FTT后的预后情况。
回顾性分析2005年1月1日至2011年12月31日期间入住我院一级烧伤/创伤转诊中心的所有NF患者。
接受FTT的患者(n = 12)与未接受FTT的患者(n = 212)在人口统计学特征上无显著差异。两组的手术次数、重症监护病房住院时间和住院时间均相同。使用的皮瓣包括10块股前外侧皮瓣、1块背阔肌皮瓣和1块桡侧前臂皮瓣。受区包括:上肢(6例)、下肢(4例)、头颈部(1例)和生殖器(1例)。未发生皮瓣失败,也无需进行回纳手术。接受FTT的患者中上肢占58.3%,而非FTT患者中上肢占18.9%(p = 0.004)。皮瓣手术平均在入院后11.6天进行,在FTT前平均进行了1.1次手术。平均FTT面积为213平方厘米。皮瓣并发症包括血清肿(n = 1)、血肿(n = 1)。供区并发症包括血肿(n = 1)、肌腱外露(n = 1)和坏死(n = 1)。
本研究表明,FTT为NF患者提供了一种有前景的重建选择,且不会对患者预后产生不利影响。