Bhattacharjee Sandipan, Goldstone Lisa, Ip Queeny, Warholak Terri
Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, AZ, USA.
Mult Scler Int. 2017;2017:3175358. doi: 10.1155/2017/3175358. Epub 2017 Apr 27.
. There is little information regarding depression treatment patterns among adults with MS and depression in ambulatory settings at national level in the United States (US). . The objectives of this study were to identify patterns and predictors of depression treatment in ambulatory settings in US among adults with MS and depression. . A cross-sectional study was conducted by pooling multiple years (2005-2011) of National Ambulatory Medical Care Survey and the outpatient department of the National Hospital Ambulatory Medical Care Survey data. The final study sample was comprised of ambulatory visits among adults with MS and depression. Dependent variable of this study was pharmacological treatment for depression with or without psychotherapy. Predictors of depression treatment were determined by conducting multivariable logistic regression. . Out of all ambulatory visits involving MS diagnosis, 20.59% also involved a depression diagnosis. Depression treatment was observed in 57.25% of the study population. Fluoxetine was the most prescribed individual antidepressant. Age and total number of chronic diseases were significant predictors of depression treatment. . Approximately six out of ten ambulatory visits involving MS and depression recorded some form of depression treatment. Future longitudinal studies should examine health outcomes associated with depression treatment in this population.
在美国全国范围内，关于患有多发性硬化症（MS）的成年人在门诊环境中抑郁症治疗模式的信息很少。本研究的目的是确定美国患有MS和抑郁症的成年人在门诊环境中抑郁症治疗的模式和预测因素。通过汇总多年（2005 - 2011年）的国家门诊医疗调查和国家医院门诊医疗调查门诊部门的数据进行了一项横断面研究。最终的研究样本包括患有MS和抑郁症的成年人的门诊就诊情况。本研究的因变量是接受或未接受心理治疗的抑郁症药物治疗。通过进行多变量逻辑回归确定抑郁症治疗的预测因素。在所有涉及MS诊断的门诊就诊中，20.59%也涉及抑郁症诊断。在57.25%的研究人群中观察到了抑郁症治疗。氟西汀是最常开具的单一抗抑郁药。年龄和慢性病总数是抑郁症治疗的重要预测因素。大约十分之六涉及MS和抑郁症的门诊就诊记录了某种形式的抑郁症治疗。未来的纵向研究应检查该人群中与抑郁症治疗相关的健康结果。
