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脑室腹腔分流术治疗儿童特发性颅内高压的疗效

Outcomes of ventriculoperitoneal shunt insertion in the management of idiopathic intracranial hypertension in children.

作者信息

Heyman J, Ved Ronak, Amato-Watkins A, Bhatti I, Te Water Naude J, Gibbon F, Leach P

机构信息

Department of Paediatric Neurosurgery, University Hospital of Wales, Cardiff, UK.

Department of Neurosurgery, University Hospital of Wales, B4 Office, Cardiff, CF14 4XW, UK.

出版信息

Childs Nerv Syst. 2017 Aug;33(8):1309-1315. doi: 10.1007/s00381-017-3423-0. Epub 2017 May 23.

DOI:10.1007/s00381-017-3423-0
PMID:28536838
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5527065/
Abstract

PURPOSE

The ventriculoperitoneal (VP) shunt has become the procedure of choice for treatment of idiopathic intracranial hypertension (IIH). We aimed to assess the efficacy of frameless stereotactic placement of VP shunts for the management of medically resistant IIH in children and to assess the role of gender and obesity in the aetiology of the condition.

METHODS

This is a retrospective analysis of the case notes of 10 patients treated surgically at the University Hospital of Wales in Cardiff, from May 2006 to September 2012.

RESULTS

VP shunts were successful in relieving headache, papilloedema and stabilising vision. No sex predilection was identified, and increased BMI was a feature throughout the population, regardless of age.

CONCLUSIONS

Neuronavigated VP shunt insertion is an effective mode of treatment for medically resistant IIH in children. The aetiological picture in children does not seem to be dominated by obesity, as in adults. Literature on childhood IIH is sparse, and larger scale, comparative studies would be of benefit to treating clinicians.

摘要

目的

脑室腹腔（VP）分流术已成为治疗特发性颅内高压（IIH）的首选方法。我们旨在评估无框架立体定向放置VP分流管治疗儿童药物抵抗性IIH的疗效，并评估性别和肥胖在该病病因中的作用。

方法

这是一项对2006年5月至2012年9月在加的夫威尔士大学医院接受手术治疗的10例患者病历的回顾性分析。

结果

VP分流术成功缓解了头痛、视乳头水肿并稳定了视力。未发现性别偏好，且无论年龄大小，整个研究人群的体重指数（BMI）均有所增加。

结论

神经导航下VP分流管置入术是治疗儿童药物抵抗性IIH的有效方法。儿童IIH的病因似乎不像成人那样以肥胖为主导。关于儿童IIH的文献较少，大规模的对比研究将有助于临床治疗医生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/be735d603bfc/381_2017_3423_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/5f9f59884389/381_2017_3423_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/65bf94d09460/381_2017_3423_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/be735d603bfc/381_2017_3423_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/5f9f59884389/381_2017_3423_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/65bf94d09460/381_2017_3423_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e40/5527065/be735d603bfc/381_2017_3423_Fig3_HTML.jpg

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