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既往机器人手术经验对腹腔镜前列腺癌根治术初始学习曲线的影响。

The influence of previous robotic experience in the initial learning curve of laparoscopic radical prostatectomy.

作者信息

Dias José Anastácio, Dall'oglio Marcos F, Colombo João Roberto, Coelho Rafael F, Nahas William Carlos

机构信息

Divisão de Urologia, Universidade de São Paulo Escola Médica, São Paulo, SP, Brasil.

出版信息

Int Braz J Urol. 2017 Sep-Oct;43(5):871-879. doi: 10.1590/S1677-5538.IBJU.2016.0526.

Abstract

INTRODUCTION

This study analyzed the impact of the experience with Robotic-Assisted Laparoscopic Prostatectomy (RALP) on the initial experience with Laparoscopic Radical Prostatectomy (LRP) by examining perioperative results and early outcomes of 110 patients. LRPs were performed by two ro-botic fellowship trained surgeons with daily practice in RALP.

PATIENTS AND METHODS

110 LRP were performed to treat aleatory selected patients. The patients were divided into 4 groups for prospective analyses. A transperitoneal approach that simulates the RALP technique was used.

RESULTS

The median operative time was 163 minutes (110-240), and this time significantly decreased through case 40, when the time plateaued (p=0.0007). The median blood loss was 250mL. No patients required blood transfusion. There were no life-threatening complications or deaths. Minor complications were uniformly distributed along the series (P=0.6401). The overall positive surgical margins (PSM) rate was 28.2% (20% in pT2 and 43.6% in pT3). PSM was in the prostate apex in 61.3% of cases. At the 12-month follow-up, 88% of men were continent (0-1 pad).

CONCLUSIONS

The present study shows that there are multiple learning curves for LRP. The shallowest learning curve was seen for the operative time. Surgeons transitioning between the RALP and LRP techniques were considered competent based on the low perioperative complication rate, absence of major complications, and lack of blood transfusions. This study shows that a learning curve still exists and that there are factors that must be considered by surgeons transitioning between the two techniques.

摘要

引言

本研究通过检查110例患者的围手术期结果和早期结局,分析了机器人辅助腹腔镜前列腺切除术(RALP)经验对腹腔镜根治性前列腺切除术(LRP)初始经验的影响。LRP由两名接受过机器人手术培训且日常进行RALP手术的外科医生实施。

患者与方法

对随机选择的患者进行了110例LRP手术。将患者分为4组进行前瞻性分析。采用了模拟RALP技术的经腹入路。

结果

中位手术时间为163分钟(110 - 240分钟),在第40例手术时时间显著下降,之后趋于平稳(p = 0.0007)。中位失血量为250mL。无患者需要输血。无危及生命的并发症或死亡。轻微并发症在整个系列中分布均匀(P = 0.6401)。总体阳性手术切缘(PSM)率为28.2%(pT2期为20%,pT3期为43.6%)。61.3%的病例PSM位于前列腺尖部。在12个月的随访中,88%的男性控尿良好(使用0 - 1片尿垫)。

结论

本研究表明LRP存在多条学习曲线。手术时间的学习曲线最浅。基于低围手术期并发症发生率、无重大并发症以及无输血情况,在RALP和LRP技术之间转换的外科医生被认为是胜任的。本研究表明学习曲线仍然存在,并且在两种技术之间转换的外科医生必须考虑一些因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4709/5678518/ccc6c1832249/1677-5538-ibju-43-05-0871-gf01.jpg

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