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多灶性原发性皮肤结节性淀粉样变性

Multifocal primary cutaneous nodular amyloidosis.

作者信息

Matsumoto Martha Emily, Collins Mary-Katharine, Raptis Anastasios, Jedrych Jaroslaw, Patton Timothy

机构信息

Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

出版信息

Dermatol Online J. 2017 May 15;23(5):13030/qt9511r6bg.

PMID:28537855
Abstract

Nodular cutaneous amyloidosis (NCA), the least common form of primary cutaneous amyloidosis, is characterized clinically by waxy, purpuric plaques and nodules and histologically by amyloid deposits in the dermis and subcutaneous tissue. We present a patient who developed multiple, non-contiguous NCA lesions over a three year period without evidence of systemic disease. We reviewed the literature and found few other cases of this unusual presentation.

摘要

结节性皮肤淀粉样变性(NCA)是原发性皮肤淀粉样变性最不常见的形式,临床特征为蜡样、紫癜性斑块和结节,组织学特征为真皮和皮下组织中有淀粉样沉积物。我们报告了一名患者,在三年时间里出现了多个不连续的NCA病变,且无全身疾病证据。我们查阅了文献,发现这种不寻常表现的其他病例很少。

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引用本文的文献

1
Localized Cutaneous Nodular Amyloidosis in a Patient with Sjögren's Syndrome.干燥综合征患者的局限性皮肤结节状淀粉样变。
Int J Mol Sci. 2023 May 28;24(11):9409. doi: 10.3390/ijms24119409.
2
Localized Cutaneous Nodular Amyloidosis: A Specific Cutaneous Manifestation of Sjögren's Syndrome.局限性皮肤结节性淀粉样变:干燥综合征的一种特异性皮肤表现。
Int J Mol Sci. 2023 Apr 17;24(8):7378. doi: 10.3390/ijms24087378.