Choi Ellie, Liau May, Huang Jingxiang, Tan Kong Bing, Aw Derrick
Division of Dermatology, Department of Medicine, National University Hospital, Singapore. ellie_
Dermatol Online J. 2017 May 15;23(5):13030/qt3xn054wf.
Basaloid follicular hamartoma (BFH) is a rare benign adnexal tumor with variable clinical presentation. We report a case of a 64-year-old man, who presented with an incidental finding of a 3mm hyperpigmented macule on his cheek. Dermoscopy revealed a structureless blue lesion. Histopathology examination showed interconnecting lobules and cords of bland pigmented epithelial cells within the dermal stroma, with the presence of pseudohorncysts. The lesional cells were faintly positive for Bcl2on immunohistochemical staining. These findings were consistent with basaloid follicular hamartoma. Histological differential diagnoses include benign lesions such as trichoepithelioma, and malignant lesions such as basal cell carcinoma (BCC).
基底样毛囊错构瘤（BFH）是一种临床表现多样的罕见良性附属器肿瘤。我们报告一例64岁男性病例，其面颊部偶然发现一个3mm的色素沉着斑。皮肤镜检查显示为无结构的蓝色损害。组织病理学检查显示真皮基质内有相互连接的小叶和条索状淡染色素上皮细胞，并存在假角质囊肿。免疫组化染色显示病变细胞Bcl2呈弱阳性。这些表现符合基底样毛囊错构瘤。组织学鉴别诊断包括良性病变如毛发上皮瘤，以及恶性病变如基底细胞癌（BCC）。
