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基底细胞样滤泡性错构瘤:病例报告及文献复习。

Basaloid follicular hamartoma: a case report and review of the literature.

机构信息

Department of Pathology and Laboratory Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

出版信息

Kaohsiung J Med Sci. 2012 Jan;28(1):57-60. doi: 10.1016/j.kjms.2011.06.034. Epub 2011 Dec 11.

Abstract

Basaloid follicular hamartoma (BFH) is a rare, benign, skin adnexal tumor. Several clinical patterns have been reported, but they all share the same histopathological features. BFH may be hereditary or nonhereditary and can be accompanied by systemic diseases. Microscopic examination of BFH shows branching cords and anastomosing strands of basaloid cells in a loose, fibrous stroma. The most important pathological differential diagnosis is infundibulocystic basal cell carcinoma. These two lesions must be differentiated carefully based on clinical presentation and histopathological picture, and even molecular studies may be needed. We present a report of a 78-year-old woman with a solitary, asymptomatic, slow-growing skin tumor on her left scalp. No associated systemic disorders were found. On the basis of an excisional biopsy performed on the tumor, a pathological diagnosis of sporadic BFH was made.

摘要

基底细胞样滤泡性错构瘤(BFH)是一种罕见的良性皮肤附属器肿瘤。已经报道了几种临床类型,但它们都具有相同的组织病理学特征。BFH 可能是遗传性的或非遗传性的,并可能伴有全身疾病。BFH 的显微镜检查显示在疏松的纤维基质中分支的索状和吻合的基底样细胞。最重要的病理鉴别诊断是漏斗部囊状基底细胞癌。这两种病变必须根据临床表现和组织病理学图像仔细区分,甚至可能需要分子研究。我们报告了一例 78 岁女性,其左侧头皮有一个单发、无症状、生长缓慢的皮肤肿瘤。未发现相关的全身疾病。根据对肿瘤进行的切除活检,病理诊断为散发性 BFH。

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