高剂量化疗后伴门静脉阻塞的胰母细胞瘤完整切除：一例报告
Complete Resection of Pancreatoblastoma With Portal Vein Obstruction After High-dose Chemotherapy: A Case Report.
作者信息
Ibuka Souji, Uehara Shuichiro, Ueno Takehisa, Oue Takaharu, Miyamura Takako, Hashii Yoshiko, Okuyama Hiroomi
机构信息
*Departments of Pediatric Surgery †Pediatrics, Osaka University Graduate School of Medicine, Yamadaoka, Suita, Osaka, Japan.
出版信息
J Pediatr Hematol Oncol. 2017 Jul;39(5):e275-e278. doi: 10.1097/MPH.0000000000000842.
BACKGROUND
As no standard chemotherapy exists for pancreatoblastoma (PB), surgical resection is the most effective way of achieving complete remission.
CASE REPORT
A 3-year-old girl with PB causing portal vein obstruction was referred to our hospital. Because of the portal vein involvement, she initially received 5 cycles of preoperative chemotherapy after biopsy, consisting of cyclophosphamide, vincristine, pirarubicin, and cisplatin. After chemotherapy, she underwent distal pancreatectomy, and the tumor was resected completely. She has been disease free for 4 years since the operation.
CONCLUSIONS
Even in cases of advanced PB, complete surgical resection with appropriate chemotherapy can lead to complete remission.
背景
由于胰腺母细胞瘤（PB）尚无标准化疗方案，手术切除是实现完全缓解的最有效方法。
病例报告
一名3岁患有PB并导致门静脉梗阻的女孩被转诊至我院。由于门静脉受累，她在活检后最初接受了5个周期的术前化疗，化疗方案包括环磷酰胺、长春新碱、吡柔比星和顺铂。化疗后，她接受了胰体尾切除术，肿瘤被完全切除。自手术以来，她已无病生存4年。
结论
即使是晚期PB病例，通过适当化疗进行完全手术切除也可实现完全缓解。
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