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实验啮齿动物运动反应的稳定性和变异性。III. 环境因素的影响及儿茶酚胺受体相关性的缺失

Stability and variability of locomotor responses of laboratory rodents. III. Effect of environmental factors and lack of catecholamine receptor correlates.

作者信息

Vetulani J, Marona-Lewicka D, Michaluk J, Popik P

机构信息

Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.

出版信息

Pol J Pharmacol Pharm. 1988 May-Jun;40(3):273-80.

PMID:2853866
Abstract

The exploratory locomotor activity of rats differs between groups, and the results suggest the involvement of a seasonal factor. The body weight and the state of satiety do not appear to influence the locomotor activity. The individual activities of rats are correlated in subsequent tests only if the period between the tests is not long. The foehn wind changes the locomotor activity in the second test, depending on the animals' experience. No correlation between the native locomotor activity and cortical and striatal binding sites for [3H]prazosin and [3H]spiroperidol was found.

摘要

大鼠的探索性运动活动在不同组之间存在差异，结果表明存在季节性因素的影响。体重和饱腹感状态似乎不影响运动活动。只有当两次测试之间的间隔时间不长时，大鼠的个体活动在后续测试中才具有相关性。焚风根据动物的经验改变第二次测试中的运动活动。未发现[3H]哌唑嗪和[3H]螺哌啶醇的天然运动活动与皮质和纹状体结合位点之间存在相关性。

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