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尚伯格病:使用秋水仙碱治疗成功的病例报告。

Schamberg's disease: case report with therapeutic success by using colchicine.

作者信息

Cavalcante Maria Lopes Lamenha Lins, Masuda Paula Yoshiko, Brito Fernanda Freitas de, Pinto Ana Cecília Versiani Duarte, Itimura Gabriela, Nunes Adauto José Ferreira

机构信息

Department of Dermatology of the Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.

出版信息

An Bras Dermatol. 2017 Mar-Apr;92(2):246-248. doi: 10.1590/abd1806-4841.20174898.

Abstract

Pigmented purpuric dermatoses (PPD) include a spectrum of diseases with different clinical aspects, but with similar histopathological features. Specific clinical findings allow the division of PPD in variants. Schamberg's disease is the most common. Treatment is sometimes ineffective and recurrences are common. There are reports of patients who responded well to the use of colchicine. We report the case of a 32-year-old woman, previously healthy, with a history of onset of asymptomatic lesions in legs. She presented purpuric skin eruptions and brownish stains diffusely distributed in the lower limbs. Biopsy was compatible with PPD. We decided for the introduction of colchicine, with good clinical response. The patient has been followed on outpatient basis for ten months without recurrence.

摘要

色素性紫癜性皮病(PPD)包括一系列具有不同临床特征但组织病理学特征相似的疾病。特定的临床发现可将PPD分为不同亚型。尚伯格病最为常见。治疗有时无效且复发常见。有报告称患者使用秋水仙碱后反应良好。我们报告一例32岁既往健康的女性病例,其腿部出现无症状皮损。她下肢出现紫癜性皮疹及弥漫分布的褐色斑。活检结果符合PPD。我们决定使用秋水仙碱,临床反应良好。该患者已门诊随访10个月,无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb08/5429115/b83bfadd965d/abd-92-02-0246-g01.jpg

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