Sardana Kabir, Sarkar Rashmi, Sehgal Virendra N
Department of Dermatology and Sexually Transmitted Disease, Lady Hardinge Medical College and Associated SK Hospital, New Delhi, India.
Int J Dermatol. 2004 Jul;43(7):482-8. doi: 10.1111/j.1365-4632.2004.02213.x.
Pigmented purpuric dermatoses are a spectrum of disorders characterized by a distinct purpuric rash, mainly localized to the lower limbs, which are morphologically dissimilar but histopathologically indistinguishable. Their etiology remains obscure. They are rather resistant to treatment. Although diagnosed quite straightforwardly, the disease entity remains an enigma and a therapeutic challenge. The current narration discusses the outline of the epidemiology, etiopathogenesis, clinical features, histopathology and management of these disorders. The current review, hopefully, may once again rekindle interest in the entity, for it has been sparingly reported or discussed for the benefit of under- and/or postgraduates and those in practice, including family physicians.
色素性紫癜性皮病是一组以独特的紫癜样皮疹为特征的疾病,主要局限于下肢,这些皮疹在形态上各不相同,但组织病理学上无法区分。其病因仍不清楚。它们对治疗相当耐药。尽管诊断相对直接,但该疾病实体仍然是一个谜,也是一个治疗挑战。本叙述讨论了这些疾病的流行病学、病因发病机制、临床特征、组织病理学和管理概述。希望本次综述能再次激发人们对该疾病实体的兴趣,因为此前针对本科生和研究生以及包括家庭医生在内的从业者的相关报道或讨论都很少。